David Leaver
  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
20182021

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  • Unearthing the Janus-face cholesterogenesis pathways in cancer

    Madan, B., Virshup, D. M., Nes, W. D. & Leaver, D. J., 16 May 2021, (E-pub ahead of print) In: Biochemical Pharmacology. p. 1-13 13 p., 114611.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
  • A nematode sterol C4α-methyltransferase catalyzes a new methylation reaction responsible for sterol diversity

    Zhou, W., Fisher, P. M., Vanderloop, B. H., Shen, Y., Shi, H., Maldonado, A. J., Leaver, D. J. & David Nes, W., 01 Feb 2020, In: Journal of Lipid Research. 61, 2, p. 192-204 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Citations (Scopus)
  • Discovery of acylsulfonohydrazide-derived inhibitors of the lysine acetyltransferase, kat6a, as potent senescence-inducing anti-cancer agents

    Priebbenow, D. L., Leaver, D. J., Nguyen, N., Cleary, B., Lagiakos, H. R., Sanchez, J., Xue, L., Huang, F., Sun, Y., Mujumdar, P., Mudududdla, R., Varghese, S., Teguh, S., Charman, S. A., White, K. L., Shackleford, D. M., Katneni, K., Cuellar, M., Strasser, J. M., Dahlin, J. L. & 13 others, Walters, M. A., Street, I. P., Monahan, B. J., Jarman, K. E., Jousset Sabroux, H., Falk, H., Chung, M. C., Hermans, S. J., Downer, N. L., Parker, M. W., Voss, A. K., Thomas, T. & Baell, J. B., 14 May 2020, In: Journal of Medicinal Chemistry. 63, 9, p. 4655-4684 30 p.

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)
  • HBO1 is required for the maintenance of leukaemia stem cells

    MacPherson, L., Anokye, J., Yeung, M. M., Lam, E. Y. N., Chan, Y. C., Weng, C. F., Yeh, P., Knezevic, K., Butler, M. S., Hoegl, A., Chan, K. L., Burr, M. L., Gearing, L. J., Willson, T., Liu, J., Choi, J., Yang, Y., Bilardi, R. A., Falk, H., Nguyen, N. & 28 others, Stupple, P. A., Peat, T. S., Zhang, M., de Silva, M., Carrasco-Pozo, C., Avery, V. M., Khoo, P. S., Dolezal, O., Dennis, M. L., Nuttall, S., Surjadi, R., Newman, J., Ren, B., Leaver, D. J., Sun, Y., Baell, J. B., Dovey, O., Vassiliou, G. S., Grebien, F., Dawson, S. J., Street, I. P., Monahan, B. J., Burns, C. J., Choudhary, C., Blewitt, M. E., Voss, A. K., Thomas, T. & Dawson, M. A., 09 Jan 2020, In: Nature. 577, 7789, p. 266-270 25 p.

    Research output: Contribution to journalArticlepeer-review

    36 Citations (Scopus)
  • Discovery of benzoylsulfonohydrazides as potent inhibitors of the histone acetyltransferase KAT6A

    Leaver, D. J., Cleary, B., Nguyen, N., Priebbenow, D. L., Lagiakos, H. R., Sanchez, J., Xue, L., Huang, F., Sun, Y., Mujumdar, P., Mudududdla, R., Varghese, S., Teguh, S., Charman, S. A., White, K. L., Katneni, K., Cuellar, M., Strasser, J. M., Dahlin, J. L., Walters, M. A. & 10 others, Street, I. P., Monahan, B. J., Jarman, K. E., Sabroux, H. J., Falk, H., Chung, M. C., Hermans, S. J., Parker, M. W., Thomas, T. & Baell, J. B., 08 Aug 2019, In: Journal of Medicinal Chemistry. 62, 15, p. 7146-7159 14 p.

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)