Calculated based on number of publications stored in Pure and citations from PlumX
1994 …2023

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Personal profile

Dr Cahill studied Science at the University of New South Wales, graduating with BSc (Hons 1) in Zoology with a strong Biochemistry emphasis in 1987 and a PhD from the Department of Pathology, School of Medicine of the University of NSW, working on the transcriptional regulation of the c-fos gene as an external student based at the Medizinische Hochschule in Hannover, Germany. After finishing his doctoral thesis in late 1994 he remained in the same lab for another twelve months as a “post doctoral scientist” (postdoc) before moving back to Australia in late 1995.

Being interested in signal transduction events in the cytoplasm, he was captivated in 1996 by the then emerging field of proteomics; so much so that he moved from Canberra back to Germany where from 04/1997 to 01/2000 he established a proteomics laboratory as postdoc/group leader at the University of Tuebingen. That activity later developed into the present Tuebingen Proteomics Centre. However before that centre was officially opened he had left the academic world to co-found a proteomics-based biotechnology company called ProteoSys AG, based in Mainz. There he remained as Chief Research Officer until 2007, after which he ‘moved back home’ to re-enter academic life in Australia. Dr Cahill commenced as a biochemistry lecturer at CSU in Wagga Wagga in 2008. Durign his time at CSU he served at different times as School Honours Coordinator, Chair of the School Research Committee, and as an elected staff representative serving on both Academic Senate and the CSU Research Committee. He taught in the areas of nutritional metabolism, biochemistry, molecular cell biology, and genomics, proteomics and bioinformatics. Dr. Cahill chose to cease employment with CSU in January 2021, and has been an adjunct academic since then. Since 2019 Dr. Cahill has also been an honorary Senior Lecturer at the Australian National University.

Dr. Cahill's research interests cover the healthy and pathological biology of the cell signalling system surrounding the protein "Progesterone Receptor Membrane Component 1". He has recently shown that PGRMC1 phosphorylation is involved in mitochondrial morphology and metabolic function, and in epigenetic gene regulation that drives cell phenotypical plasticity. PGRMC1's phosphorylated tyrosines appeared in evolution at the same time as the gastrulation organiser and derived specialised cell types, such as neurons. We are begining to understand the broad range of effects of PGRMC1 in diseases like cancer (Warburg effect metabolism) and neurodegeneration. For instance, it is emerging that Alzheimer's disease may be caused by perturbations in PGRMC1 function, which cause all of the downstream effects commonly researched (amyloid beta, Tau. ApoE, epigentics, glucose metabolism, and mitochondrial dysfunction). The future will attest whether these unorthodox statements bear the test of time (no other Australian Alzheimer's researcher would argue this). Dr. Cahill is confident that it will be so.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Pathology/Molecular Cell Biology, Ph.D., Structural and functional analyses of the Serum Response Factor, University of New South Wales

Feb 1991Aug 1994

Award Date: 06 Feb 1996

Zoology and Biochemistry, B.Sc.(Hons 1), Bachelor of Science, University of New South Wales


Award Date: 09 May 1988

External positions

Honorary Senior Lecturer (, The Australian National University

07 Jan 2019 → …

Scientific Advisory Board (, Cognition Therapeutics Inc., Pittsburgh

Aug 2013 → …

Chief Research Officer and Scientific Co-founder, ProteoSys AG, Mainz

Feb 2002Sept 2007

Postdoctoral Research Group Leader, Proteomics, Interfaculty Institute for Cell Biology, University of Tuebingen

Apr 1997Jan 2000

Postdoctoral Researcher, John Curtin School of Medical Research, Australian National University

Jan 1996Feb 1997

Postdoctoral Researcher, Hannover Medical School

Aug 1994Nov 1995

Subject keywords

  • PGRMC1
  • MAPR
  • steroid biology
  • molecular evolution
  • Alzheimer's disease
  • cancer
  • metabolism
  • synaptic plasticity


Dive into the research topics where Mike Cahill is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or