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20142022

Research activity per year

Personal profile

Personal profile

I have extensive research expertise with mouse and human models of colon cancer, with a focus on Wnt signalling, a molecular pathway that is critical for stem cell function. I completed my PhD in the Vincan group at the University of Melbourne, studying the function of a Wnt receptor, Frizzled7, in the normal intestinal epithelium, at the initiation of colon cancer and during tumour morphogenesis. I developed novel ex-vivo 3D tumour organoid technologies to dissect the transition from stem cell to cancer stem cell.

In my most recent Postdoc position at QUT in the Hepaticgenomics Research Group, I established a hepatic spheroid model to use in an assay to test potential anti-fibrotic compounds.

Within the Gulbali Institute, my research focus has shifted to Biosecurity and the investigation into anti-virals. I plan to use my expertise in 3D cell cultures to establish methods for interrogating and testing potential anti-viral compounds.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Molecular Oncology, Doctor of Philosophy, The role of Frizzled-7 in the normal intestinal epithelium and colorectal cancer, The University of Melbourne

Award Date: 29 Jul 2017

External positions

Honorary Researcher, The University of Melbourne

01 Aug 201931 Jul 2024

Subject keywords

  • 3D cell culture
  • organoids
  • biosecurity
  • anti-virals
  • crystallography

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