A Comprehensive Evaluation of the Bruker Biotyper MS and Vitek MS Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Systems for Identification of Yeasts, Part of the National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) Study, 2012 to 2013

He Wang, Yan Yan Fan, Timothy Kudinha, Zhi Peng Xu, Meng Xiao, Li Zhang, Xin Fan, Fanrong Kong, Ying Chun Xu

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)
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Abstract

Among the 2,683 yeast isolates representing 41 different species (25 Candida and Candida-related species and 16 non-Candida yeast species) collected in the National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) program (2012 to 2013), the Bruker Biotyper MS matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) system exhibited significantly higher accuracy rates than the Vitek MS system for identification of all yeast isolates (98.8% versus 95.4%, P <0.001 by Pearson's chi-square test) and for all Candida and Candida-related species isolates (99.4% versus 95.5%, P < 0.001).

Original languageEnglish
Pages (from-to)1376-1380
Number of pages5
JournalJournal of Clinical Microbiology
Volume54
Issue number5
DOIs
Publication statusPublished - 01 May 2016

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