A rare case of haemangiopericytoma in an Amazon Parrot

Panayiotis Loukopoulos, Anastasia Komnenou, Vasilios Tsiouris, Michael Zavlaris, A.-L. Thomas, I. Georgopoulou

Research output: Contribution to journalMeeting Abstract

Abstract

A 20-year-old male Amazon parrot (Amazona ochrocephala) was presented with a history of a painless mass developing over six months. On clinical examination a firm, well defined, 2.52cm mass was palpated at the right pelvic area. Haematology and biochemistry were normal while radiography revealed that there was no bone involvement. The tumour was removed under general anaesthesia. The bird recovered fully and remains tumourfree two years post-surgery. The tumour was ovoid, whitish and moderately hard in cut section. Histologically, the mass was well demarcated and composed of spindle or fusiform cells sparsely arranged in perivascular whorls or in loose interlacing bundles, giving the lesion a translucent appearance. Tumour cells were mildly pleomorphic with few mitoses. Based on the above, a diagnosis of benign haemangiopericytoma was offered, the first reported in this species. However, haemangiopericytoma, which is usually reported in dogs, is mainly composed of polygonal or spindle cells with uniform, ovoid, plump nuclei in that species. Furthermore, the presence of small wavy spindle cells partly arranged in interlacing bundles, albeit not a dominant feature, was reminiscent of a benign peripheral nerve sheath tumour (BPNST/ schwannoma) and allowed this diagnosis to be entertained. For this reason, immunohistochemistry was performed employing a streptavidin-biotin-peroxidase protocol. Tumour cells were positive for S-100 and aSMA but not GFAP. Most cells arranged perivascularly or in bundles were positive for PCNA and vimentin, suggesting that they belong to the same tumour cell population. The immunohistochemical profile was consistent with and further established the diagnosis of haemangiopericytoma. This report demonstrates the value of immunohistochemistry, through the application of a specific panel of antibodies, in differentiating between haemangiopericytoma and BPNST.
Original languageEnglish
Pages (from-to)E26-E27
Number of pages2
JournalVeterinary Clinical Pathology
Volume38
Issue numbers1
Publication statusPublished - 2009
EventEuropean Society of Veterinary Clinical Pathology (ESVCP) and European College of Veterinary (ESVCP) Clinical Pathology (ECVCP) 11th Annual Congress - Thessaloniki, Greece
Duration: 07 Oct 200909 Oct 2009

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Amazona
Hemangiopericytoma
parrots
neoplasms
immunohistochemistry
cells
streptavidin
Neoplasms
peripheral nerves
vimentin
hematology
biotin
radiography
lesions (animal)
biochemistry
clinical examination
mitosis
Immunohistochemistry
anesthesia
peroxidase

Cite this

Loukopoulos, P., Komnenou, A., Tsiouris, V., Zavlaris, M., Thomas, A-L., & Georgopoulou, I. (2009). A rare case of haemangiopericytoma in an Amazon Parrot. Veterinary Clinical Pathology, 38(s1), E26-E27.
Loukopoulos, Panayiotis ; Komnenou, Anastasia ; Tsiouris, Vasilios ; Zavlaris, Michael ; Thomas, A.-L. ; Georgopoulou, I. / A rare case of haemangiopericytoma in an Amazon Parrot. In: Veterinary Clinical Pathology. 2009 ; Vol. 38, No. s1. pp. E26-E27.
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Loukopoulos, P, Komnenou, A, Tsiouris, V, Zavlaris, M, Thomas, A-L & Georgopoulou, I 2009, 'A rare case of haemangiopericytoma in an Amazon Parrot', Veterinary Clinical Pathology, vol. 38, no. s1, pp. E26-E27.

A rare case of haemangiopericytoma in an Amazon Parrot. / Loukopoulos, Panayiotis; Komnenou, Anastasia; Tsiouris, Vasilios; Zavlaris, Michael; Thomas, A.-L.; Georgopoulou, I.

In: Veterinary Clinical Pathology, Vol. 38, No. s1, 2009, p. E26-E27.

Research output: Contribution to journalMeeting Abstract

TY - JOUR

T1 - A rare case of haemangiopericytoma in an Amazon Parrot

AU - Loukopoulos, Panayiotis

AU - Komnenou, Anastasia

AU - Tsiouris, Vasilios

AU - Zavlaris, Michael

AU - Thomas, A.-L.

AU - Georgopoulou, I.

PY - 2009

Y1 - 2009

N2 - A 20-year-old male Amazon parrot (Amazona ochrocephala) was presented with a history of a painless mass developing over six months. On clinical examination a firm, well defined, 2.52cm mass was palpated at the right pelvic area. Haematology and biochemistry were normal while radiography revealed that there was no bone involvement. The tumour was removed under general anaesthesia. The bird recovered fully and remains tumourfree two years post-surgery. The tumour was ovoid, whitish and moderately hard in cut section. Histologically, the mass was well demarcated and composed of spindle or fusiform cells sparsely arranged in perivascular whorls or in loose interlacing bundles, giving the lesion a translucent appearance. Tumour cells were mildly pleomorphic with few mitoses. Based on the above, a diagnosis of benign haemangiopericytoma was offered, the first reported in this species. However, haemangiopericytoma, which is usually reported in dogs, is mainly composed of polygonal or spindle cells with uniform, ovoid, plump nuclei in that species. Furthermore, the presence of small wavy spindle cells partly arranged in interlacing bundles, albeit not a dominant feature, was reminiscent of a benign peripheral nerve sheath tumour (BPNST/ schwannoma) and allowed this diagnosis to be entertained. For this reason, immunohistochemistry was performed employing a streptavidin-biotin-peroxidase protocol. Tumour cells were positive for S-100 and aSMA but not GFAP. Most cells arranged perivascularly or in bundles were positive for PCNA and vimentin, suggesting that they belong to the same tumour cell population. The immunohistochemical profile was consistent with and further established the diagnosis of haemangiopericytoma. This report demonstrates the value of immunohistochemistry, through the application of a specific panel of antibodies, in differentiating between haemangiopericytoma and BPNST.

AB - A 20-year-old male Amazon parrot (Amazona ochrocephala) was presented with a history of a painless mass developing over six months. On clinical examination a firm, well defined, 2.52cm mass was palpated at the right pelvic area. Haematology and biochemistry were normal while radiography revealed that there was no bone involvement. The tumour was removed under general anaesthesia. The bird recovered fully and remains tumourfree two years post-surgery. The tumour was ovoid, whitish and moderately hard in cut section. Histologically, the mass was well demarcated and composed of spindle or fusiform cells sparsely arranged in perivascular whorls or in loose interlacing bundles, giving the lesion a translucent appearance. Tumour cells were mildly pleomorphic with few mitoses. Based on the above, a diagnosis of benign haemangiopericytoma was offered, the first reported in this species. However, haemangiopericytoma, which is usually reported in dogs, is mainly composed of polygonal or spindle cells with uniform, ovoid, plump nuclei in that species. Furthermore, the presence of small wavy spindle cells partly arranged in interlacing bundles, albeit not a dominant feature, was reminiscent of a benign peripheral nerve sheath tumour (BPNST/ schwannoma) and allowed this diagnosis to be entertained. For this reason, immunohistochemistry was performed employing a streptavidin-biotin-peroxidase protocol. Tumour cells were positive for S-100 and aSMA but not GFAP. Most cells arranged perivascularly or in bundles were positive for PCNA and vimentin, suggesting that they belong to the same tumour cell population. The immunohistochemical profile was consistent with and further established the diagnosis of haemangiopericytoma. This report demonstrates the value of immunohistochemistry, through the application of a specific panel of antibodies, in differentiating between haemangiopericytoma and BPNST.

KW - comparative oncology

KW - veterinary oncology

KW - Veterinary pathology

KW - veterinary surgery

KW - avian diseases

M3 - Meeting Abstract

VL - 38

SP - E26-E27

JO - Veterinary Clinical Pathology

JF - Veterinary Clinical Pathology

SN - 0275-6382

IS - s1

ER -

Loukopoulos P, Komnenou A, Tsiouris V, Zavlaris M, Thomas A-L, Georgopoulou I. A rare case of haemangiopericytoma in an Amazon Parrot. Veterinary Clinical Pathology. 2009;38(s1):E26-E27.