Accessing Polyoxygenated Dibenzofurans via the Union of Phenols and o-Benzoquinones: Rapid Syntheses of Metabolites Isolated from Ribes takare

Meng Yao Zhang, Russell A. Barrow

Research output: Contribution to journalLetterpeer-review

26 Citations (Scopus)

Abstract

The construction of polyoxygenated dibenzo[b,d]furan frameworks from the union of substituted phenols/naphthols and o-benzoquinones via a Michael-oxidation-oxa-Michael cascade is reported. The power of this transformation is demonstrated in the generation of a library of highly substituted dibenzofurans, featuring specifically substituted molecules containing broad ranges of functionality. The utility of this method is showcased in the total syntheses of two dibenzofurans isolated from Ribes takare, assembling the carbon scaffold of both natural products in one operation.

Original languageEnglish
Pages (from-to)2302-2305
Number of pages4
JournalOrganic Letters
Volume19
Issue number9
DOIs
Publication statusPublished - 05 May 2017

Fingerprint

Dive into the research topics of 'Accessing Polyoxygenated Dibenzofurans via the Union of Phenols and o-Benzoquinones: Rapid Syntheses of Metabolites Isolated from Ribes takare'. Together they form a unique fingerprint.

Cite this