Acute Schistosomiasis

Li Yuesheng, Allen G.P. Ross

    Research output: Book chapter/Published conference paperChapter (peer-reviewed)peer-review

    1 Citation (Scopus)


    Katayama syndrome is an early clinical manifestation of schistosomiasis that occurs several weeks post-infection with Schistosoma spp. (trematode) worms. Because of this temporal delay and its non-specific presentation, it is the form of schistosomiasis most likely to be misdiagnosed by travel medicine physicians and infectious disease specialists in non-endemic countries. Katayama syndrome appears between 14-84 days after non-immune individuals are exposed to first schistosome infection or heavy reinfection. Disease onset appears to be related to migrating schistosomula and egg deposition with individuals typically presenting with nocturnal fever, cough, myalgia, headache and abdominal tenderness. Serum antibodies and schistosome egg excretion often substantiate infection if detected. Diffuse pulmonary infiltrates are found radio logically and almost all cases have eosinophilia and a history of water contact before presentation of clinical symptoms. Patients respond well to regimens of praziquantel with and without steroids. Artemisinin treatment given early after exposure may decrease the risk of the syndrome.
    Original languageEnglish
    Title of host publicationSchistosoma
    Subtitle of host publicationBiology, pathology, and control
    EditorsBarrie G.M. Jamieson
    Place of PublicationBoca Raton, FL
    PublisherCRC Press
    Number of pages8
    ISBN (Electronic)9781498744263
    ISBN (Print)9781498744256
    Publication statusPublished - 2016


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