Acute subendocardial ischaemia leads to homogenous prolongation in ventricular repolarization

Long-Le Ma, Lexin Wang

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Abstract

Acute transmural ischaemia often shortens ventricular repolarization and increases repolarization dispersion, leading to life threatening ventricular arrhythmias in animal models and human subjects. Experimental studies and clinical observations have shown that acute subendocardial ischaemia rarely causes serious ventricular arrhythmia. We hypothesized that the different arrhythmia outcomes between transmural and subendocardial ischaemia are largely due to the homogenous prolongation in ventricular repolarization after acute subendocardial ischaemia.
Original languageEnglish
Pages (from-to)137-139
Number of pages3
JournalMedical Hypotheses
Volume68
Issue number1
DOIs
Publication statusPublished - 2006

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