An allelopathic compound from festuca spp. as a lead molecule for development of pre-emergent herbicides for weed management

Craig Stewart, Russell Barrow, Sajid Latif, Leslie A. Weston

Research output: Other contribution to conferenceAbstract

Abstract

There is a great need for the development of herbicides with novel modes of action, due to increasing evolution of herbicide resistance in common weed species and the lack new modes of action in commercial herbicides introduced in recent years.1-3 Certain cultivars of fine leaved fescue (Festuca spp.) grasses are known to interfere with the growth of other plants by exudation of a phytotoxic non-protein amino acid, m-tyrosine, into the rhizosphere.4,5 However, m-tyrosine is highly susceptible to microbial degradation and so is potentially unsuited for use as a commercial soil-applied pre-emergence herbicide. We have synthesised several analogues based on the bioactive architecture of this natural product, with improved herbicidal activity and will evaluate extended environmental half-life, and investigate potential mode(s) of action.
Original languageEnglish
Pages314
Number of pages1
Publication statusPublished - 10 Aug 2018
Event34th Annual Meeting of the International Society of Chemical Ecology - Budapest Congress Center, Budapest, Hungary
Duration: 12 Aug 201818 Aug 2018
https://www.chemecol.org/pastmeetings.shtml

Conference

Conference34th Annual Meeting of the International Society of Chemical Ecology
CountryHungary
CityBudapest
Period12/08/1818/08/18
Internet address

Fingerprint

Festuca
weed control
herbicides
tyrosine
mechanism of action
nonprotein amino acids
herbicide resistance
exudation
biodegradation
half life
weeds
plant growth
grasses
cultivars
soil

Cite this

Stewart, C., Barrow, R., Latif, S., & Weston, L. A. (2018). An allelopathic compound from festuca spp. as a lead molecule for development of pre-emergent herbicides for weed management. 314. Abstract from 34th Annual Meeting of the International Society of Chemical Ecology, Budapest, Hungary.
Stewart, Craig ; Barrow, Russell ; Latif, Sajid ; Weston, Leslie A. / An allelopathic compound from festuca spp. as a lead molecule for development of pre-emergent herbicides for weed management. Abstract from 34th Annual Meeting of the International Society of Chemical Ecology, Budapest, Hungary.1 p.
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Stewart, C, Barrow, R, Latif, S & Weston, LA 2018, 'An allelopathic compound from festuca spp. as a lead molecule for development of pre-emergent herbicides for weed management', 34th Annual Meeting of the International Society of Chemical Ecology, Budapest, Hungary, 12/08/18 - 18/08/18 pp. 314.

An allelopathic compound from festuca spp. as a lead molecule for development of pre-emergent herbicides for weed management. / Stewart, Craig; Barrow, Russell; Latif, Sajid; Weston, Leslie A.

2018. 314 Abstract from 34th Annual Meeting of the International Society of Chemical Ecology, Budapest, Hungary.

Research output: Other contribution to conferenceAbstract

TY - CONF

T1 - An allelopathic compound from festuca spp. as a lead molecule for development of pre-emergent herbicides for weed management

AU - Stewart, Craig

AU - Barrow, Russell

AU - Latif, Sajid

AU - Weston, Leslie A.

PY - 2018/8/10

Y1 - 2018/8/10

N2 - There is a great need for the development of herbicides with novel modes of action, due to increasing evolution of herbicide resistance in common weed species and the lack new modes of action in commercial herbicides introduced in recent years.1-3 Certain cultivars of fine leaved fescue (Festuca spp.) grasses are known to interfere with the growth of other plants by exudation of a phytotoxic non-protein amino acid, m-tyrosine, into the rhizosphere.4,5 However, m-tyrosine is highly susceptible to microbial degradation and so is potentially unsuited for use as a commercial soil-applied pre-emergence herbicide. We have synthesised several analogues based on the bioactive architecture of this natural product, with improved herbicidal activity and will evaluate extended environmental half-life, and investigate potential mode(s) of action.

AB - There is a great need for the development of herbicides with novel modes of action, due to increasing evolution of herbicide resistance in common weed species and the lack new modes of action in commercial herbicides introduced in recent years.1-3 Certain cultivars of fine leaved fescue (Festuca spp.) grasses are known to interfere with the growth of other plants by exudation of a phytotoxic non-protein amino acid, m-tyrosine, into the rhizosphere.4,5 However, m-tyrosine is highly susceptible to microbial degradation and so is potentially unsuited for use as a commercial soil-applied pre-emergence herbicide. We have synthesised several analogues based on the bioactive architecture of this natural product, with improved herbicidal activity and will evaluate extended environmental half-life, and investigate potential mode(s) of action.

M3 - Abstract

SP - 314

ER -

Stewart C, Barrow R, Latif S, Weston LA. An allelopathic compound from festuca spp. as a lead molecule for development of pre-emergent herbicides for weed management. 2018. Abstract from 34th Annual Meeting of the International Society of Chemical Ecology, Budapest, Hungary.