An idea to explore: Visualization of ionization of amino acids using Mathematica

Research output: Contribution to journalArticlepeer-review

3 Downloads (Pure)

Abstract

Ionization of amino acids (AA) is very important concept in biochemistry. We
integrate the mathematical concept of probability with biochemically relevant
process of AA ionization. We visualize the ionization process with Mathematica
software discussing intramolecular interactions between weakly acidic/basic functional
groups and charge–pH variation of amino acids in water solution. The visualizations
rely on the notion of probability of ionization of functional groups and
demonstrate how the extent of ionization and charge varies with pH of the solution.
The examples described include amino acids and weak diprotic acids and
bases. The aim is to help students better appreciate the importance and consequences
of AA ionization and correct some misconceptions.
Original languageEnglish
Pages (from-to)333-345
JournalBiochemistry and Molecular Biology Education
Volume49
Issue number3
Publication statusPublished - 2021

Fingerprint

Dive into the research topics of 'An idea to explore: Visualization of ionization of amino acids using Mathematica'. Together they form a unique fingerprint.

Cite this