ANKH polymorphisms and clicking of the temporomandibular joint in dental residents

Boyen Huang; Katsu Takahashi; Tomoko Goto; Honoka Kiso; Manabu Sugai; Akira Shimizu; Shinji Kosugi; Kazuhisa Bessho

doi:10.1007/s12663-014-0622-z

ANKH polymorphisms and clicking of the temporomandibular joint in dental residents

Boyen Huang, Katsu Takahashi, Tomoko Goto, Honoka Kiso, Manabu Sugai, Akira Shimizu, Shinji Kosugi, Kazuhisa Bessho

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of "ANKH inorganic pyrophosphate transport regulator'' (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques.Results The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7-66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p >= 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.

Original language	English
Pages (from-to)	247-251
Number of pages	5
Journal	Journal of Maxillofacial and Oral Surgery
Volume	14
Issue number	2
Early online date	2014
DOIs	https://doi.org/10.1007/s12663-014-0622-z
Publication status	Published - Jun 2015

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title = "ANKH polymorphisms and clicking of the temporomandibular joint in dental residents",

abstract = "Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of {"}ANKH inorganic pyrophosphate transport regulator'' (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques.Results The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7-66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p >= 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.",

keywords = "Temporomandibular disorders, Clicking, ANKH, Polymorphism, Oral surgeon",

author = "Boyen Huang and Katsu Takahashi and Tomoko Goto and Honoka Kiso and Manabu Sugai and Akira Shimizu and Shinji Kosugi and Kazuhisa Bessho",

note = "Includes bibliographical references.",

year = "2015",

month = jun,

doi = "10.1007/s12663-014-0622-z",

language = "English",

volume = "14",

pages = "247--251",

journal = "Journal of Maxillofacial and Oral Surgery",

issn = "0972-8279",

publisher = "Springer India",

number = "2",

}

TY - JOUR

T1 - ANKH polymorphisms and clicking of the temporomandibular joint in dental residents

AU - Huang, Boyen

AU - Takahashi, Katsu

AU - Goto, Tomoko

AU - Kiso, Honoka

AU - Sugai, Manabu

AU - Shimizu, Akira

AU - Kosugi, Shinji

AU - Bessho, Kazuhisa

N1 - Includes bibliographical references.

PY - 2015/6

Y1 - 2015/6

N2 - Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of "ANKH inorganic pyrophosphate transport regulator'' (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques.Results The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7-66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p >= 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.

AB - Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of "ANKH inorganic pyrophosphate transport regulator'' (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques.Results The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7-66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p >= 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.

KW - Temporomandibular disorders

KW - Clicking

KW - ANKH

KW - Polymorphism

KW - Oral surgeon

U2 - 10.1007/s12663-014-0622-z

DO - 10.1007/s12663-014-0622-z

M3 - Article

C2 - 26028843

SN - 0972-8279

VL - 14

SP - 247

EP - 251

JO - Journal of Maxillofacial and Oral Surgery

JF - Journal of Maxillofacial and Oral Surgery

IS - 2

ER -

ANKH polymorphisms and clicking of the temporomandibular joint in dental residents

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