Objective: To investigate the impact of anxiety symptoms on the circadian rhythm of blood pressure in patients with hypertension. Methods: The 24 h ambulatory blood pressure was compared between patients with hypertension and generalized anxiety disorder, and patients with hypertension only. Results: The mean day-time and night-time systolic (SBP, 156.6±11.0 and 149.6±12.4 mm Hg, respectively) blood pressure in patients with both hypertension and anxiety was greater than in patients with hypertension only (143.2±15.0 and 126.0±10.8 mm Hg, respectively, P<0.01). The mean day-time and night-time diastolic blood pressure (DBP, 101.5±10.1 and 96.9±17.6 mm Hg, respectively) in the hypertension and anxiety group was also greater than in the hypertension only patients (94.1±10.9 and 77.4±10.2 mm Hg, respectively, P<0.01). SBP and DBP dipping was found in 87.5% and 80.1% of the hypertension only patients, as compared with 16.6% and 21.4% respectively, of the hypertension and anxiety patients (P<0.01). Conclusions: The presence of anxiety symptoms is associated with a higher level of blood pressure in hypertensive patients. Anxiety symptoms are also associated with a diminished circadian rhythm of blood pressure. The clinical significance of the reduced blood pressure dipping at night requires further investigation.
|Number of pages||4|
|Journal||International Journal of Psychiatry in Clinical Practice|
|Publication status||Published - 2008|