Assessing the health implications of UV/LED nail lamp radiation exposure during manicure and pedicure procedures: A scoping review

Skin malignancies associated with radiation exposure, notably malignant melanoma and keratinocyte carcinoma, are emerging as a significant global health challenge. While indoor tanning beds are associated with skin cancer risk, limited research exists on ultraviolet (UV)/light-emitting diode (LED) nail lamps used widely in manicures/pedicures. This scoping review aimed to synthesize evidence on the health effects of UV/LED nail lamp exposure during manicures/pedicures. A systematic search of PubMed, Scopus, and CINAHL identified 17 articles, including 12 studies and 5 case reports meeting eligibility criteria published in English from inception to January 2024. Several studies characterized emitted spectra and measured irradiances from commercial lamps, finding predominantly UVA emissions that complied with safety guidelines when correctly used. However, higher exposures exceeding safety limits were also observed. In vitro evidence demonstrated that UV nail lamps potentially induce DNA damage consistent with carcinogenesis. Case reports described squamous cell carcinoma and actinic keratosis restricted to the hands of patients with histories of extensive UV nail lamp exposure. While studies suggested that the cancer risks from typical use are acceptably low, there is room for improvement. Measurements have shown that the doses of UV emission vary across different lamps yet remain low. Surveys have revealed a need for more consumer awareness regarding these risks. Current evidence is insufficient to support the mandatory implementation of protective measures such as gloves or sunscreen during UV nail lamp exposure. More importantly, a direct causal link between UV nail lamps and carcinoma development has not been conclusively established.