BFDV Vaccination Trial: an update

Nicolai Bonne, Patrick Shearer, Margaret Sharp, Phillip Clark, Shane Raidal

Research output: Book chapter/Published conference paperConference paperpeer-review

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Psittacine beak and feather disease is a significant disease of both captive and wild psittacine birds worldwide (ref). Vaccination has proven an effective means of controlling the causative agent; beak and feather disease virus (BFDV)(Raidal et al., 1993). There have been attempts at culturing BFDV in numerous cell culture systems, however there have been no reports of successful virus amplification using cell cultures (Pass and Perry, 1985) and past vaccination trials have utilized virus eluted from feathers of infected birds (Raidal et al., 1993). Therefore, full length recombinant BFDV capsid protein was expressed using a baculovirus expression system. This recombinant protein has previously been proven to react with anti-BFDV sera from naturally immune psittacines and from chickens experimentally inoculated with native BFDV in both western immuno-blots and haemagglutination inhibition (HI) assay (Stewart et al., 2007). However, the use of baculovirus expressed recombinant protein for vaccination against BFDV has not been documented. Thus, we tested the protective properties of this recombinant protein using a flock of BFDV-free long-billed corellas (Cacatua tenurostris) (n=18).
Original languageEnglish
Title of host publicationAdvancing and Promoting Avian Medicine and Stewardship
EditorsGarry Cross
Place of PublicationMelbourne, Australia
Number of pages6
Publication statusPublished - 2007
EventAssociation of Avian Veterinarians Australasian Committee (AAVAC) Annual Conference - Melbourne, Vic. Australia, Australia
Duration: 03 Oct 200706 Oct 2007


ConferenceAssociation of Avian Veterinarians Australasian Committee (AAVAC) Annual Conference


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