Bioactive Compounds in Canola Meal

    Research output: ThesisDoctoral Thesis

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    Canola meal, is a by-product of oil extraction and is of comparatively lowvalue. This meal may have additional value in the biotechnology, food and biomedical fields, if potential health beneficial bioactive compounds with the ability to combat several modern day ailments can be identified.The present study was undertaken to characterise the phenolic compounds (PC) and protease inhibitors (PIs) from canola meal extracts (CMEs) using two genotypes and assess their potential bioactivities. Both qualitative and quantitative analyses were employed for the determination of PI activities and total phenolic contents (TPC). Furthermore, the bioactive properties of the CMEs were studied, focusing principally on antioxidant and chemopreventive (topoisomerase inhibition) properties, as well as antihypertension, antidiabetic and antipliase/antiadipogenic activities. In addition, an in vitro system was used to assess antiadipogenic activity employing C3H10T1/2 stem cells.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • Charles Sturt University
    • Blanchard, Christopher, Co-Supervisor
    • Rehman, Ata, Co-Supervisor
    • Luckett, David, Co-Supervisor
    • Obied, Hassan, Co-Supervisor
    Award date30 Oct 2015
    Place of PublicationAustralia
    Publication statusPublished - 2015


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