Bioactivity and structure of biophenols as mediators of chronic diseases

Greg Tucker, Kevin Robards

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)
296 Downloads (Pure)


Biophenols and their associated activity have generated intense interest. Current topics of debate are their bioavailability and bioactivity. It is generally assumed that their plasma concentrations are insufficient to produce the health benefits previously attributed to their consumption. However, data on localised in vivo concentrations are not available and many questions remain unanswered. Potential mechanisms by which they may exert significant bioactivity are discussed together with structure activity relationships. Biophenols are highly reactive species and they can react with a range of other compounds. Products of their reaction when functioning as antioxidants are examined.
Original languageEnglish
Pages (from-to)929-966
Number of pages38
JournalCritical Reviews in Food Science and Nutrition
Issue number10
Publication statusPublished - 2008


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