A single isomer in an eight isomer menthol mixture was acylated through a lipase mediated transesterification. The isomer selected was the commercially attractive L-menthol. This protocol constitutes a simple method for selecting a commercially attractive isomer from a complex mixture to enable production of the pure form.
Brady, D., Reddy, S., Mboniswa, B., Steenkamp, L. H., Rousseau, A. L., Parkinson, C., Chaplin, J., Mitra, R. K., Moutlana, T., Marais, S. F., & Gardiner, N. S. (2012). Biocatalytic enantiomeric resolution of L-menthol from an eight isomeric menthol mixture through transesterification. Journal of Molecular Catalysis - B Enzymatic, 75, 1-10. https://doi.org/10.1016/j.molcatb.2011.10.011