Indocyanine green was used to determine the blood volume of galahs (Eolophus roseicapillus). Plasma clearance and retention of a single intravenous bolus dose of indocyanine green was measured in duplicate in 10 galahs of mixed age and gender. Indocyanine green was administered intravenously at 0.5 mg/kg, and blood samples were collected at 3, 6, and 9 minutes after injection. The light absorbance of the plasma at 805 nm was measured by spectrophotometer. Blood volume and clearance values were determined from the initial linear portion of the clearance curves. Percentage blood volume (mean ± SD) was 10.61 ± 2.92% of body weight. The half-life of indocyanine green was 5.42 ± 0.76 minutes; the fractional excretion, 13.0 ± 1.56% per minute; the plasma clearance, 5.92 ± 1.87 ml/min/kg; and the 9-minute percentage retention, 12.2 ± 9%.
|Number of pages||4|
|Journal||Journal of Avian Medicine and Surgery|
|Publication status||Published - 01 Dec 1998|