Canine plasma cortisol and CRP concentrations related to surgeon experience

Research output: Other contribution to conferenceAbstract

Abstract

In veterinary medicine plasma cortisol and CRP have both been used as surgical stress markers since the mid 1990s.This study compared the increases in the levels of both markers in relation to surgeon experience postovariohysterectomy. Forty five female pound dogs were ovariohysterectomised by randomly assigned surgeons, withthirty seven sterilised by veterinary undergraduate students and eight by veterinary surgeons with greater than 10 yearsexperience. A standard anaesthesia and analgesia protocol was used, with all bitches sterilised through a ventral midlineapproach. Blood samples were collected immediately preoperatively (T0), and at 2 hours (T1), 4 hours (T2) and 6 hours(T3) post operatively.The higher CRP concentrations seen in dogs sterilised by inexperienced surgeons suggests that inexperienced surgeonscause more tissue trauma and secondary inflammation as a result of their surgical technique than do experiencedsurgeons. The study points to a number of potential areas where this could occur, namely blood loss and surgical time. The lack of a significant difference between cortisol increases between surgeon groups reflects the large number offactors involved in changes in blood cortisol concentrations and potentially that there is relatively little differencebetween the groups of surgeons in terms of the perceived pain suffered by the patient undergoing an openovariohysterectomy. Potential limitations of this study include the limited sample size and allowing inclusion of onlylimited explanatory variables.The samples were analysed for cortisol and CRP concentrations and the data was analysed usinga linear mixed model fitted to log10 (CRP/cortisol) with time and surgeon as fixed effects and dog as a random effect.Compared to experienced surgeons, inexperienced surgeons were found to have longer surgery times (average 86 minversus 19 min), longer anaesthesia times (130 versus 49 minutes) and more intra-operative blood loss (19ml versus 6ml). CRP was found to i
Original languageEnglish
Pages12
Number of pages1
Publication statusPublished - 2011
Event2011 ACVSc Science Week - Gold Coast, Australia
Duration: 01 Jan 2011 → …

Conference

Conference2011 ACVSc Science Week
CountryAustralia
Period01/01/11 → …

Fingerprint Dive into the research topics of 'Canine plasma cortisol and CRP concentrations related to surgeon experience'. Together they form a unique fingerprint.

  • Cite this

    Michelsen, J. (2011). Canine plasma cortisol and CRP concentrations related to surgeon experience. 12. Abstract from 2011 ACVSc Science Week, Australia.