Clinical risk and cardiac biomarkers associated with diagnosis and adverse events in prehospital non-ST- segment elevation acute coronary syndrome patients: A scoping review

Joshua D. Bampton, Brian Sengstock, Peter Micalos

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Research into prehospital risk mitigation using clinical risk
scores in conjunction with biomarker analysis is lacking.

Aims: This research aimed to identify the extent, range and nature of literature
surrounding clinical risk in acute coronary syndrome and adverse cardiac
events within the prehospital setting.

Methods: This study applied the JBI scoping review methodology to identify peer-reviewed scientific literature published from January 2000 to August 2022. Articles were obtained from searches of two electronic databases, CINAHL Plus and MEDLINE (Ovid). The search results were filtered and selected for analysis
through the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) statement.

Results: The initial search yielded a total of 234 results. Of these, 154 were screened resulting in a final total of 10 articles from which clinical risk scores and prehospital cardiac biomarkers were highlighted for discussion.

Conclusion: Clinical risk scores provide practitioners with a foundation for risk analysis when assessing a patient with suspected acute coronary syndrome. The most effective risk-score method to predict major adverse cardiac events was
the HEART score. Technological advances in biomarker analysis may assist
when used in conjunction with risk scores.
Original languageEnglish
Pages (from-to)60 - 67
Number of pages8
JournalJournal of Paramedic Practice: the clinical monthly for emergency care professionals
Volume17
Issue number2
DOIs
Publication statusE-pub ahead of print - Feb 2025

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