Combination fibrinolytic therapy in the treatment of chronic septic pleuropneumonia in a Thoroughbred gelding.

David Rendle, Susan Armstrong, Kristopher Hughes

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

This report documents the treatment of a case of chronic pleuropneumonia in a 3-year-old Thoroughbred gelding. A recombinant tissue plasminogen activator (tenecteplase) and a recombinant deoxyribonucleic acidase (alphadornase) were infused into the pleural cavity as adjunctive therapy in the early stages of treatment. Instillation of fibrinolytic drugs was associated with a subjective reduction in the amount of fibrin deposition and decreased fluid accumulation within the pleural cavities. Fibrinolytic therapy may be a useful adjunctive therapy in selected cases of intrapleural disease in horses.
Original languageEnglish
Pages (from-to)358-362
Number of pages5
JournalAustralian Veterinary Journal
Volume90
Issue number9
DOIs
Publication statusPublished - Sep 2012

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