Comparison of human chorionic gonadotropin (hCG), deslorelin, deslorelin combined with hCG, and histrelin to induce ovulation in the mare

J.B. Chopin, V.J. Brookes, J. Rodger, A. Gunn

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Administering hCG induces ovulation at a me-dian of 36 hours [1] in 82-89% of mares [2]. No difference was foundbetween buserelin and deslorelin [3], nor histrelin to hCG in theinterval to ovulation [4]. Deslorelin (liquid vehicle) has equal effi-cacy to hCG and pelleted deslorelin in inducing ovulation [5, 6]. AnhCG/deslorelin combination is used in clinical practice, with onereportfinding no difference in ovulation rate between hCG;deslorelin; and the combination of hCG/deslorelin [7]. This studycompared hCG/deslorelin combination to hCG, deslorelin and his-trelin and a placebo. The null hypotheses tested were: 1) There is nodifference in days to ovulation between“ovulating inducing drugs”and a placebo; and 2) There is no difference in days to ovulationbetween the hCG/deslorelin combination and hCG, deslorelin and histrelin.
Original languageEnglish
Article number03095
Pages (from-to)73-74
Number of pages2
JournalJournal of Equine Veterinary Science
Volume89
DOIs
Publication statusE-pub ahead of print - 17 Jun 2020

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