TY - JOUR
T1 - CSF amyloid β42 and tau levels correlate with AIDS dementia complex
AU - Brew, Bruce J.
AU - Pemberton, L.
AU - Blennow, K.
AU - Wallin, A.
AU - Hagberg, L.
PY - 2005/11/8
Y1 - 2005/11/8
N2 - There is concern that AIDS dementia complex (ADC) may be complicated by Alzheimer disease (AD). Because AD presence and risk are related to CSF β-amyloid (1-42) (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau), the authors examined these in ADC, AD, and controls. ADC had significantly decreased CSF Aβ42 and increased t-tau and p-tau concentrations similar to AD, suggesting that ADC may be associated with AD or an AD-like process.
AB - There is concern that AIDS dementia complex (ADC) may be complicated by Alzheimer disease (AD). Because AD presence and risk are related to CSF β-amyloid (1-42) (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau), the authors examined these in ADC, AD, and controls. ADC had significantly decreased CSF Aβ42 and increased t-tau and p-tau concentrations similar to AD, suggesting that ADC may be associated with AD or an AD-like process.
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U2 - 10.1212/01.wnl.0000183293.95787.b7
DO - 10.1212/01.wnl.0000183293.95787.b7
M3 - Article
C2 - 16275845
AN - SCOPUS:27644524501
SN - 0028-3878
VL - 65
SP - 1490
EP - 1492
JO - Neurology
JF - Neurology
IS - 9
ER -