CSF amyloid β42 and tau levels correlate with AIDS dementia complex

Bruce J. Brew, L. Pemberton, K. Blennow, A. Wallin, L. Hagberg

Research output: Contribution to journalArticlepeer-review

133 Citations (Scopus)

Abstract

There is concern that AIDS dementia complex (ADC) may be complicated by Alzheimer disease (AD). Because AD presence and risk are related to CSF β-amyloid (1-42) (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau), the authors examined these in ADC, AD, and controls. ADC had significantly decreased CSF Aβ42 and increased t-tau and p-tau concentrations similar to AD, suggesting that ADC may be associated with AD or an AD-like process.
Original languageEnglish
Pages (from-to)1490-1492
Number of pages3
JournalNeurology
Volume65
Issue number9
DOIs
Publication statusPublished - 08 Nov 2005

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