We consider equations that represent a constancy condition for a 2D Wronskian, mixed Wronskian-Casoratian and 2D Casoratian. These determinantal equations are shown to have the number of independent integrals equal to their order-this implies Darboux integrability. On the other hand, the recurrent formulae for the leading principal minors are equivalent to the 2D Toda equation and its semi-discrete and lattice analogues with particular boundary conditions (cut-off constraints). This connection is used to obtain recurrent formulae and closed-form expressions for integrals of the Toda-type equations from the integrals of the determinantal equations. General solutions of the equations corresponding to vanishing determinants are given explicitly while, in the non-vanishing case, they are given in terms of solutions of ordinary linear equations.