Digoxin therapy in the elderly: Pharmacokinetic considerations in nursing

Herbert Jelinek, Paul Warner

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)
108 Downloads (Pure)


Digoxin is effective in controlling ventricular rhythm in atrial fibrillation and is used in heart failure when angiotensin converting enzyme inhibitors and diuretics are not effective. Due to the use of more than one drug often required with these conditions, pharmacokinetic considerations are important including complementary medicine. An increased awareness of drug action in the elderly is important as there is often an increase in body fat and leaner muscle mass as well as changes in organ function such as the kidney, which changes the drug activity. Nurses have an important role to play in the safe administration of digoxin.
Original languageEnglish
Pages (from-to)263-269
Number of pages7
JournalGeriatric Nursing
Issue number4
Publication statusPublished - Jul 2011


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