Dose dependent effects of exogenous vitamin D3 Metabolite 1,25(OH)2D3 during bone development

Vivek Pande

Research output: ThesisMasters Thesis

68 Downloads (Pure)

Abstract

The biologically active form of vitamin D 3 is 1,25(OH)2D3 which is involved in mineral homeostasis and bone formation. Deficiency of vitamin D3 is a major cause of bone disorders in poultry. The use of supplementary dietary vitamin D3 to combat this problem is growing and is well documented for adult birds, however there is a paucity of literature on how vitamin D3 modulates bone growth in avian species. In order to determine the role of Vitamin D3 during embryonic osteogenesis, this study examined the effects of low and high doses of vitamin D3, by in ovo and in vitro administration, on osteogenic differentiation of chicken mesenchymal stem cells.
Original languageEnglish
QualificationMaster of Philosophy
Awarding Institution
  • Charles Sturt University
Supervisors/Advisors
  • Quinn, Jane, Principal Supervisor
  • Chousalkar, Kapil, Co-Supervisor
Award date01 Dec 2013
Place of PublicationAustralia
Publisher
Publication statusPublished - 2013

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