Effect of autologous adipose-derived mesenchymal stem cell therapy in the treatment of a post-traumatic chondral defect of the knee

Julien Freitag, Douglas Li, James Wickham, Kiran Shah, Abi Tenen

Research output: Contribution to journalArticle

15 Citations (Scopus)
10 Downloads (Pure)

Abstract

Isolated chondral defects have a limited capacity to heal and predispose to the development of osteoarthritis. Current surgical management can be unpredictable in outcome. Improved understanding of the action of mesenchymal stem cells (MSCs) has seen renewed interest in their role in cartilage repair. A 26-year-old athlete presented with a post-traumatic, isolated patella chondral defect. The patient underwent an arthroscopy with removal of a chondral loose body. After failure to symptomatically improve 12 months following surgery, the patient received intra-articular autologous adipose-derived mesenchymal stem cell (ADMSC) therapy.

Original languageEnglish
Article number220852
Pages (from-to)1-8
Number of pages8
JournalBMJ Case Reports
Volume2017
DOIs
Publication statusPublished - Oct 2017

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