TY - JOUR
T1 - Effect of chamomile on the complications of cancer
T2 - A systematic review
AU - Maleki, Maryam
AU - Mardani, Abbas
AU - Manouchehri, Mehdi
AU - Ashghali Farahani, Mansoureh
AU - Vaismoradi, Mojtaba
AU - Glarcher, Manela
N1 - Publisher Copyright:
© The Author(s) 2023.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Background and objectives: Despite significant advances in the diagnosis and treatment of cancer, many people across the world still suffer from this chronic disease and its complications. Chamomile as an herbal medicine has gained an increasing attention for relieving cancer complications. This study aimed to integrate and synthesize current international evidence regarding the effect of chamomile on cancer complications. Methods: A systematic review was undertaken. Five online databases including Web of Science, PubMed [including MEDLINE], Cochrane Library, Scopus, and Embase were searched and articles published from inception to January 2023 were retrieved. All clinical trials and similar interventional studies on human subjects examining the effects of chamomile on cancer complications were included in the review and research synthesis. Relevant data were extracted from eligible studies after quality appraisals using proper methodological tools. The review results were presented narratively given that meta-analysis was impossible. Results: A total of 2240 studies were retrieved during the search process, but 18 articles were selected. The total sample size was 1099 patients with cancer of which 622 participants were female. Fifteen studies used an RCT design. Various forms of chamomile were used such as mouthwash, topical material, tea, capsule, syrup and aromatherapy massage. Chamomile effectively reduced oral mucositis, skin complications, depression, and vomiting and also improved appetite and quality of life among cancer patients. Conclusion: The use of chamomile as a non-pharmacologic and safe method can be helpful for mitigating cancer complications in patients with cancer. Therefore, it can be incorporated into routine care along with other therapeutic measures to reduce patients’ suffering related to cancer.
AB - Background and objectives: Despite significant advances in the diagnosis and treatment of cancer, many people across the world still suffer from this chronic disease and its complications. Chamomile as an herbal medicine has gained an increasing attention for relieving cancer complications. This study aimed to integrate and synthesize current international evidence regarding the effect of chamomile on cancer complications. Methods: A systematic review was undertaken. Five online databases including Web of Science, PubMed [including MEDLINE], Cochrane Library, Scopus, and Embase were searched and articles published from inception to January 2023 were retrieved. All clinical trials and similar interventional studies on human subjects examining the effects of chamomile on cancer complications were included in the review and research synthesis. Relevant data were extracted from eligible studies after quality appraisals using proper methodological tools. The review results were presented narratively given that meta-analysis was impossible. Results: A total of 2240 studies were retrieved during the search process, but 18 articles were selected. The total sample size was 1099 patients with cancer of which 622 participants were female. Fifteen studies used an RCT design. Various forms of chamomile were used such as mouthwash, topical material, tea, capsule, syrup and aromatherapy massage. Chamomile effectively reduced oral mucositis, skin complications, depression, and vomiting and also improved appetite and quality of life among cancer patients. Conclusion: The use of chamomile as a non-pharmacologic and safe method can be helpful for mitigating cancer complications in patients with cancer. Therefore, it can be incorporated into routine care along with other therapeutic measures to reduce patients’ suffering related to cancer.
KW - cancer
KW - chamomile
KW - complication
KW - non-pharmacologic methods
KW - systematic review
KW - Humans
KW - Plant Extracts/administration & dosage
KW - Male
KW - Quality of Life
KW - Female
KW - Neoplasms/complications
KW - Stomatitis/therapy
KW - Chamomile
KW - Massage/methods
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UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=woscharlessturt_pure&SrcAuth=WosAPI&KeyUT=WOS:000971123000001&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.1177/15347354231164600
DO - 10.1177/15347354231164600
M3 - Review article
C2 - 37052390
AN - SCOPUS:85152605027
SN - 1534-7354
VL - 22
JO - Integrative Cancer Therapies
JF - Integrative Cancer Therapies
ER -