Effect of hyperglycemia on cardiac autonomic function in type 2 diabetes

Mika P. Tarvainen; Jukka A. Lipponen; Hayder Al-Aubaidy; Herbert Jelinek

Effect of hyperglycemia on cardiac autonomic function in type 2 diabetes

Mika P. Tarvainen, Jukka A. Lipponen, Hayder Al-Aubaidy, Herbert Jelinek

Research output: Book chapter/Published conference paper › Conference paper › peer-review

Abstract

Heart rate variability (HRV) is reduced in diabetes mellitus (DM) patients, suggesting dysfunction of cardiac autonomic regulation which has been associated with increased risk for cardiac events. In this paper, we examined the associations of blood glucose level (BGL) and duration of diabetes with autonomic nervous system (ANS) function assessed by HRV analysis. Resting HRV and BGL measures of 32 healthy controls and 54 type 2 DM (T2DM) patients were analyzed. HRV data were analyzed using time-domain, frequency-domain and nonlinear methods. HRV parameters showed a clear difference between controls and T2DM patients. BGL correlated negatively with mean RR interval. In addition, a decrease in HRV was observed in hyperglycemia, most clear changes shown in triangular interpolation of RR interval histogram (TINN), root mean square of successive RR interval differences (RMSSD) and Poincaré plot index SD1. Duration of diabetes was clearly associated with decreased HRV, shown by decreases in standard deviation of RR intervals (SDNN), HRV triangular index (HRVi), TINN, LF power and Poincaré plot index SD2. Glycemic values were not associated with disease duration.

Original language	English
Title of host publication	Computing in Cardiology 2012
Subtitle of host publication	Volume 39
Place of Publication	United States
Publisher	IEEE, Institute of Electrical and Electronics Engineers
Pages	405-408
Number of pages	4
Volume	39
ISBN (Electronic)	9781467320764
ISBN (Print)	9781467320740
Publication status	Published - 2012
Event	39th Computing in Cardiology Conference, CinC 2012 - AGH University of Science and Technology, Krakow, Poland Duration: 09 Sept 2012 → 12 Sept 2012 https://web.archive.org/web/20120719150718/http://www.cinc2012.org/ (Conference website) http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=6414852 (Conference proceedings)

Conference

Conference	39th Computing in Cardiology Conference, CinC 2012
Country/Territory	Poland
City	Krakow
Period	09/09/12 → 12/09/12
Other	Computing in Cardiology provides an international forum for scientists and professionals from the fields of medicine, physics, engineering and computer science, and has been held annually since 1974.
Internet address	https://web.archive.org/web/20120719150718/http://www.cinc2012.org/ (Conference website) http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=6414852 (Conference proceedings)

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Cite this

@inproceedings{793c020236144f8eb9e9399ff26d3af0,

title = "Effect of hyperglycemia on cardiac autonomic function in type 2 diabetes",

abstract = "Heart rate variability (HRV) is reduced in diabetes mellitus (DM) patients, suggesting dysfunction of cardiac autonomic regulation which has been associated with increased risk for cardiac events. In this paper, we examined the associations of blood glucose level (BGL) and duration of diabetes with autonomic nervous system (ANS) function assessed by HRV analysis. Resting HRV and BGL measures of 32 healthy controls and 54 type 2 DM (T2DM) patients were analyzed. HRV data were analyzed using time-domain, frequency-domain and nonlinear methods. HRV parameters showed a clear difference between controls and T2DM patients. BGL correlated negatively with mean RR interval. In addition, a decrease in HRV was observed in hyperglycemia, most clear changes shown in triangular interpolation of RR interval histogram (TINN), root mean square of successive RR interval differences (RMSSD) and Poincar{\'e} plot index SD1. Duration of diabetes was clearly associated with decreased HRV, shown by decreases in standard deviation of RR intervals (SDNN), HRV triangular index (HRVi), TINN, LF power and Poincar{\'e} plot index SD2. Glycemic values were not associated with disease duration.",

keywords = "Blood, Correlation, Diseases, Frequency domain analysis, Heart rate variability, Diabetes",

author = "Tarvainen, {Mika P.} and Lipponen, {Jukka A.} and Hayder Al-Aubaidy and Herbert Jelinek",

year = "2012",

language = "English",

isbn = "9781467320740",

volume = "39",

pages = "405--408",

booktitle = "Computing in Cardiology 2012",

publisher = "IEEE, Institute of Electrical and Electronics Engineers",

address = "United States",

note = "39th Computing in Cardiology Conference, CinC 2012 ; Conference date: 09-09-2012 Through 12-09-2012",

url = "https://web.archive.org/web/20120719150718/http://www.cinc2012.org/, http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=6414852",

}

Tarvainen, MP, Lipponen, JA, Al-Aubaidy, H & Jelinek, H 2012, Effect of hyperglycemia on cardiac autonomic function in type 2 diabetes. in Computing in Cardiology 2012: Volume 39. vol. 39, IEEE, Institute of Electrical and Electronics Engineers, United States, pp. 405-408, 39th Computing in Cardiology Conference, CinC 2012, Krakow, Poland, 09/09/12. <http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6420416&tag=1>

Effect of hyperglycemia on cardiac autonomic function in type 2 diabetes. / Tarvainen, Mika P.; Lipponen, Jukka A.; Al-Aubaidy, Hayder et al.
Computing in Cardiology 2012: Volume 39. Vol. 39 United States: IEEE, Institute of Electrical and Electronics Engineers, 2012. p. 405-408.

Research output: Book chapter/Published conference paper › Conference paper › peer-review

TY - GEN

T1 - Effect of hyperglycemia on cardiac autonomic function in type 2 diabetes

AU - Tarvainen, Mika P.

AU - Lipponen, Jukka A.

AU - Al-Aubaidy, Hayder

AU - Jelinek, Herbert

PY - 2012

Y1 - 2012

N2 - Heart rate variability (HRV) is reduced in diabetes mellitus (DM) patients, suggesting dysfunction of cardiac autonomic regulation which has been associated with increased risk for cardiac events. In this paper, we examined the associations of blood glucose level (BGL) and duration of diabetes with autonomic nervous system (ANS) function assessed by HRV analysis. Resting HRV and BGL measures of 32 healthy controls and 54 type 2 DM (T2DM) patients were analyzed. HRV data were analyzed using time-domain, frequency-domain and nonlinear methods. HRV parameters showed a clear difference between controls and T2DM patients. BGL correlated negatively with mean RR interval. In addition, a decrease in HRV was observed in hyperglycemia, most clear changes shown in triangular interpolation of RR interval histogram (TINN), root mean square of successive RR interval differences (RMSSD) and Poincaré plot index SD1. Duration of diabetes was clearly associated with decreased HRV, shown by decreases in standard deviation of RR intervals (SDNN), HRV triangular index (HRVi), TINN, LF power and Poincaré plot index SD2. Glycemic values were not associated with disease duration.

AB - Heart rate variability (HRV) is reduced in diabetes mellitus (DM) patients, suggesting dysfunction of cardiac autonomic regulation which has been associated with increased risk for cardiac events. In this paper, we examined the associations of blood glucose level (BGL) and duration of diabetes with autonomic nervous system (ANS) function assessed by HRV analysis. Resting HRV and BGL measures of 32 healthy controls and 54 type 2 DM (T2DM) patients were analyzed. HRV data were analyzed using time-domain, frequency-domain and nonlinear methods. HRV parameters showed a clear difference between controls and T2DM patients. BGL correlated negatively with mean RR interval. In addition, a decrease in HRV was observed in hyperglycemia, most clear changes shown in triangular interpolation of RR interval histogram (TINN), root mean square of successive RR interval differences (RMSSD) and Poincaré plot index SD1. Duration of diabetes was clearly associated with decreased HRV, shown by decreases in standard deviation of RR intervals (SDNN), HRV triangular index (HRVi), TINN, LF power and Poincaré plot index SD2. Glycemic values were not associated with disease duration.

KW - Blood

KW - Correlation

KW - Diseases

KW - Frequency domain analysis

KW - Heart rate variability, Diabetes

M3 - Conference paper

SN - 9781467320740

VL - 39

SP - 405

EP - 408

BT - Computing in Cardiology 2012

PB - IEEE, Institute of Electrical and Electronics Engineers

CY - United States

T2 - 39th Computing in Cardiology Conference, CinC 2012

Y2 - 9 September 2012 through 12 September 2012

ER -

Effect of hyperglycemia on cardiac autonomic function in type 2 diabetes

Abstract

Conference

UN SDGs

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