Efficacy of a morantel-abamectin combination for the treatment of resistant ascarids in foals

Edwina Wilkes; F F McConaghy; Renee Thompson; K Dawson; Nicholas Sangster; Kristopher Hughes

doi:10.1111/avj.12559

Efficacy of a morantel-abamectin combination for the treatment of resistant ascarids in foals

Edwina Wilkes, F F McConaghy, Renee Thompson, K Dawson, Nicholas Sangster, Kristopher Hughes

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Background

This study was performed to investigate the efficacy of a morantel–abamectin combination for the treatment of macrocyclic lactone (ML)-resistant Parascaris spp. infections in foals.

Methods

Foals on five properties with a Parascaris faecal egg count (FEC) > 50 eggs per gram were used to estimate the FEC reduction (FECR) and efficacy of the anthelmintic combination.

Results & Conclusion

On all properties, resistance to ivermectin and abamectin was present and the Parascaris FECR in foals administered the morantel–abamectin combination was > 99%, indicating that this combination effectively controlled ML-resistant parasites.

Original language	English
Pages (from-to)	85-88
Number of pages	3
Journal	Australian Veterinary Journal
Volume	95
Issue number	3
Early online date	Feb 2017
DOIs	https://doi.org/10.1111/avj.12559
Publication status	Published - Mar 2017

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10.1111/avj.12559

FAECAL EGG COUNT VARIABILITY IN FOALS AND PARASITE CONTROL PRACTICES IN AUSTRALIA
Hughes, K. (Principal Supervisor)
Mar 2013 → Mar 2017
Activity: Supervision/Examination/Mentoring › Internal HDR Supervision

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title = "Efficacy of a morantel-abamectin combination for the treatment of resistant ascarids in foals",

abstract = " Background This study was performed to investigate the efficacy of a morantel–abamectin combination for the treatment of macrocyclic lactone (ML)-resistant Parascaris spp. infections in foals. Methods Foals on five properties with a Parascaris faecal egg count (FEC) > 50 eggs per gram were used to estimate the FEC reduction (FECR) and efficacy of the anthelmintic combination. Results & Conclusion On all properties, resistance to ivermectin and abamectin was present and the Parascaris FECR in foals administered the morantel–abamectin combination was > 99%, indicating that this combination effectively controlled ML-resistant parasites. ",

keywords = "anthelmintics, horses, Parascaris spp, resistance, roundworms",

author = "Edwina Wilkes and McConaghy, {F F} and Renee Thompson and K Dawson and Nicholas Sangster and Kristopher Hughes",

note = "Imported on 12 Apr 2017 - DigiTool details were: Journal title (773t) = Australian Veterinary Journal. ISSNs: 1751-0813; ",

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doi = "10.1111/avj.12559",

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journal = "Australian Veterinary Journal",

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T1 - Efficacy of a morantel-abamectin combination for the treatment of resistant ascarids in foals

AU - Wilkes, Edwina

AU - McConaghy, F F

AU - Thompson, Renee

AU - Dawson, K

AU - Sangster, Nicholas

AU - Hughes, Kristopher

N1 - Imported on 12 Apr 2017 - DigiTool details were: Journal title (773t) = Australian Veterinary Journal. ISSNs: 1751-0813;

PY - 2017/3

Y1 - 2017/3

N2 - Background This study was performed to investigate the efficacy of a morantel–abamectin combination for the treatment of macrocyclic lactone (ML)-resistant Parascaris spp. infections in foals. Methods Foals on five properties with a Parascaris faecal egg count (FEC) > 50 eggs per gram were used to estimate the FEC reduction (FECR) and efficacy of the anthelmintic combination. Results & Conclusion On all properties, resistance to ivermectin and abamectin was present and the Parascaris FECR in foals administered the morantel–abamectin combination was > 99%, indicating that this combination effectively controlled ML-resistant parasites.

AB - Background This study was performed to investigate the efficacy of a morantel–abamectin combination for the treatment of macrocyclic lactone (ML)-resistant Parascaris spp. infections in foals. Methods Foals on five properties with a Parascaris faecal egg count (FEC) > 50 eggs per gram were used to estimate the FEC reduction (FECR) and efficacy of the anthelmintic combination. Results & Conclusion On all properties, resistance to ivermectin and abamectin was present and the Parascaris FECR in foals administered the morantel–abamectin combination was > 99%, indicating that this combination effectively controlled ML-resistant parasites.

KW - anthelmintics

KW - horses

KW - Parascaris spp

KW - resistance

KW - roundworms

U2 - 10.1111/avj.12559

DO - 10.1111/avj.12559

M3 - Article

C2 - 28239856

SN - 1751-0813

VL - 95

SP - 85

EP - 88

JO - Australian Veterinary Journal

JF - Australian Veterinary Journal

IS - 3

ER -

Efficacy of a morantel-abamectin combination for the treatment of resistant ascarids in foals

Abstract

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FAECAL EGG COUNT VARIABILITY IN FOALS AND PARASITE CONTROL PRACTICES IN AUSTRALIA

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