Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

Tony J Kenna; Stuart I Davidson; Ran Duan; Linda A Bradbury; Janelle McFarlane; Malcolm Smith; Helen Weedon; Shayna Street; Ranjeny Thomas; Gethin P Thomas; Matthew A. Brown

doi:10.1002/art.33507

Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

Tony J Kenna, Stuart I Davidson, Ran Duan, Linda A Bradbury, Janelle McFarlane, Malcolm Smith, Helen Weedon, Shayna Street, Ranjeny Thomas, Gethin P Thomas, Matthew A. Brown

Research output: Contribution to journal › Article › peer-review

222 Citations (Scopus)

Abstract

Ankylosing spondylitis (AS) is a common inflammatory arthritis affecting primarily the axial skeleton. IL23R is genetically associated with AS. This study was undertaken to investigate and characterize the role of interleukin-23 (IL-23) signaling in AS pathogenesis.

Original language	English
Pages (from-to)	1420-1429
Number of pages	10
Journal	Arthritis and Rheumatism
Volume	64
Issue number	5
DOIs	https://doi.org/10.1002/art.33507
Publication status	Published - 2012

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Kenna, T. J., Davidson, S. I., Duan, R., Bradbury, L. A., McFarlane, J., Smith, M., Weedon, H., Street, S., Thomas, R., Thomas, G. P., & Brown, M. A. (2012). Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis. Arthritis and Rheumatism, 64(5), 1420-1429. https://doi.org/10.1002/art.33507

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title = "Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis",

abstract = "Ankylosing spondylitis (AS) is a common inflammatory arthritis affecting primarily the axial skeleton. IL23R is genetically associated with AS. This study was undertaken to investigate and characterize the role of interleukin-23 (IL-23) signaling in AS pathogenesis.",

author = "Kenna, {Tony J} and Davidson, {Stuart I} and Ran Duan and Bradbury, {Linda A} and Janelle McFarlane and Malcolm Smith and Helen Weedon and Shayna Street and Ranjeny Thomas and Thomas, {Gethin P} and Brown, {Matthew A.}",

year = "2012",

doi = "10.1002/art.33507",

language = "English",

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Kenna, TJ, Davidson, SI, Duan, R, Bradbury, LA, McFarlane, J, Smith, M, Weedon, H, Street, S, Thomas, R, Thomas, GP & Brown, MA 2012, 'Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis', Arthritis and Rheumatism, vol. 64, no. 5, pp. 1420-1429. https://doi.org/10.1002/art.33507

TY - JOUR

T1 - Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

AU - Kenna, Tony J

AU - Davidson, Stuart I

AU - Duan, Ran

AU - Bradbury, Linda A

AU - McFarlane, Janelle

AU - Smith, Malcolm

AU - Weedon, Helen

AU - Street, Shayna

AU - Thomas, Ranjeny

AU - Thomas, Gethin P

AU - Brown, Matthew A.

PY - 2012

Y1 - 2012

N2 - Ankylosing spondylitis (AS) is a common inflammatory arthritis affecting primarily the axial skeleton. IL23R is genetically associated with AS. This study was undertaken to investigate and characterize the role of interleukin-23 (IL-23) signaling in AS pathogenesis.

AB - Ankylosing spondylitis (AS) is a common inflammatory arthritis affecting primarily the axial skeleton. IL23R is genetically associated with AS. This study was undertaken to investigate and characterize the role of interleukin-23 (IL-23) signaling in AS pathogenesis.

U2 - 10.1002/art.33507

DO - 10.1002/art.33507

M3 - Article

SN - 2326-5191

VL - 64

SP - 1420

EP - 1429

JO - Arthritis and Rheumatism

JF - Arthritis and Rheumatism

IS - 5

ER -

Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

Abstract

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