Abstract
BACKGROUND:Infection with Shigella spp. is common among diarrhea patients in Southeast Asia regions and most isolates found in these regions are known to be multi-drug resistant. A multicentre study of Shigella spp. in six Asian countries found Shigella flexneri isolates to be resistance to ciprofloxacin in China, Pakistan and Vietnam. The Cambodian Demographic Health Survey in 2005 reported 20% of children under five have diarrhea, while 3% presented with bloody. However, the burden of the disease cause by Shigella sp. among those diarrhea patients was not well described due to limitations in the researchg system, microbiology laboratories, and documentation. According to Cambodian Ministry of Health (MoH) treatment guidelines for referral hospitals, trimethoprim-sulfamethoxazole is the first line treatment while amoxicillin or ciprofloxacin are the second line for treatment of Shigellosis. The sensitivity of Shigella spp. to the recommended antibiotics is currently unknown in Cambodian patients. OBJECTIVE:The purpose of this study is to publish the first data from Cambodian patients infected with Shigella spp. in term of proportion and antimicrobial susceptibility characteristics among those isolated.
Original language | English |
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Title of host publication | The 4th International Conference on Public Health among Greater Mekong Sub-regional Countries |
Publisher | The 4th International Conference on Public Health among Greater Mekong Sub-regional Countries |
Publication status | Published - 2012 |