Evaluation of Masimo signal extraction technology pulse oximetry in anaesthetised pregnant sheep

Christopher Quinn, Anthea L. Raisis, Gabrielle C. Musk

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective: Evaluation of the accuracy of Masimo Signal Extraction Technology (SET) pulse oximetry in anaesthetized late gestational pregnant sheep.Study Design: Prospective experimental study.Animals: 17 pregnant merino ewes.Methods: Animals included in study were late gestation ewes undergoing general anaesthesia for caesarean delivery or foetal surgery in a medical research laboratory. Masimo Radical-7 pulse oximetry (SpO2) measurements were compared to co-oximetry (SaO2) measurements from arterial blood gas analyses. The failure rate of the pulse oximeter was calculated. Accuracy was assessed by Bland and Altman's (2007) limits of agreement method. The effect of mean arterial blood pressure (MAP), perfusion index (PI) and haemoglobin (Hb) concentration on accuracy were assessed by regression analysis.Results: Forty arterial blood samples paired with SpO2 and blood pressure measurements were obtained. SpO2 ranged from 42 ' 99 % and SaO2 from 43.7 ' 99.9%. MAP ranged from 24 24 ' 82 mmHg, PI from 0.1 ' 1.56 and Hb concentration from 71 - 114 g L-1. Masimo pulse oximetry measurements tended to underestimate oxyhaemoglobin saturation compared to co-oximetry with a bias (mean difference) of -2% and precision (standard deviation of the differences) of 6%. Accuracy appeared to decrease when SpO2 was less than 75%, however numbers were too small for statistical comparisons. Hb concentration and PI had no significant effect on accuracy, whereas MAP was negatively correlated with SpO2 bias.Conclusions: and clinical relevance Masimo SET pulse oximetry can provide reliable and continuous monitoring of oxyhaemoglobin saturation in anaesthetized pregnant sheep during clinically relevant levels of cardiopulmonary dysfunction. Further work is needed to assess pulse oximeter function during extreme hypotension and hypoxaemia.
Original languageEnglish
Pages (from-to)149-156
Number of pages8
JournalVeterinary Anaesthesia and Analgesia
Volume40
Issue number2
DOIs
Publication statusPublished - Mar 2013

Fingerprint

Oximetry
Sheep
Arterial Pressure
blood pressure
Technology
sheep
hemoglobin
Oxyhemoglobins
Hemoglobins
Perfusion
ewes
hypotension
biomedical research
blood gases
Merino
Blood Gas Analysis
heart rate
hypoxia
anesthesia
animals

Cite this

@article{899743048a244f9e8299858a2d3c29de,
title = "Evaluation of Masimo signal extraction technology pulse oximetry in anaesthetised pregnant sheep",
abstract = "Objective: Evaluation of the accuracy of Masimo Signal Extraction Technology (SET) pulse oximetry in anaesthetized late gestational pregnant sheep.Study Design: Prospective experimental study.Animals: 17 pregnant merino ewes.Methods: Animals included in study were late gestation ewes undergoing general anaesthesia for caesarean delivery or foetal surgery in a medical research laboratory. Masimo Radical-7 pulse oximetry (SpO2) measurements were compared to co-oximetry (SaO2) measurements from arterial blood gas analyses. The failure rate of the pulse oximeter was calculated. Accuracy was assessed by Bland and Altman's (2007) limits of agreement method. The effect of mean arterial blood pressure (MAP), perfusion index (PI) and haemoglobin (Hb) concentration on accuracy were assessed by regression analysis.Results: Forty arterial blood samples paired with SpO2 and blood pressure measurements were obtained. SpO2 ranged from 42 ' 99 {\%} and SaO2 from 43.7 ' 99.9{\%}. MAP ranged from 24 24 ' 82 mmHg, PI from 0.1 ' 1.56 and Hb concentration from 71 - 114 g L-1. Masimo pulse oximetry measurements tended to underestimate oxyhaemoglobin saturation compared to co-oximetry with a bias (mean difference) of -2{\%} and precision (standard deviation of the differences) of 6{\%}. Accuracy appeared to decrease when SpO2 was less than 75{\%}, however numbers were too small for statistical comparisons. Hb concentration and PI had no significant effect on accuracy, whereas MAP was negatively correlated with SpO2 bias.Conclusions: and clinical relevance Masimo SET pulse oximetry can provide reliable and continuous monitoring of oxyhaemoglobin saturation in anaesthetized pregnant sheep during clinically relevant levels of cardiopulmonary dysfunction. Further work is needed to assess pulse oximeter function during extreme hypotension and hypoxaemia.",
keywords = "Anaesthesia, Pregnancy, Pulse oximetry, Sheep",
author = "Christopher Quinn and Raisis, {Anthea L.} and Musk, {Gabrielle C.}",
note = "Imported on 12 Apr 2017 - DigiTool details were: month (773h) = March, 2013; Journal title (773t) = Veterinary Anaesthesia and Analgesia. ISSNs: 1467-2995;",
year = "2013",
month = "3",
doi = "10.1111/j.1467-2995.2012.00772.x",
language = "English",
volume = "40",
pages = "149--156",
journal = "Veterinary Anaesthesia and Analgesia",
issn = "1351-6574",
publisher = "Wiley-Blackwell",
number = "2",

}

Evaluation of Masimo signal extraction technology pulse oximetry in anaesthetised pregnant sheep. / Quinn, Christopher; Raisis, Anthea L.; Musk, Gabrielle C.

In: Veterinary Anaesthesia and Analgesia, Vol. 40, No. 2, 03.2013, p. 149-156.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Evaluation of Masimo signal extraction technology pulse oximetry in anaesthetised pregnant sheep

AU - Quinn, Christopher

AU - Raisis, Anthea L.

AU - Musk, Gabrielle C.

N1 - Imported on 12 Apr 2017 - DigiTool details were: month (773h) = March, 2013; Journal title (773t) = Veterinary Anaesthesia and Analgesia. ISSNs: 1467-2995;

PY - 2013/3

Y1 - 2013/3

N2 - Objective: Evaluation of the accuracy of Masimo Signal Extraction Technology (SET) pulse oximetry in anaesthetized late gestational pregnant sheep.Study Design: Prospective experimental study.Animals: 17 pregnant merino ewes.Methods: Animals included in study were late gestation ewes undergoing general anaesthesia for caesarean delivery or foetal surgery in a medical research laboratory. Masimo Radical-7 pulse oximetry (SpO2) measurements were compared to co-oximetry (SaO2) measurements from arterial blood gas analyses. The failure rate of the pulse oximeter was calculated. Accuracy was assessed by Bland and Altman's (2007) limits of agreement method. The effect of mean arterial blood pressure (MAP), perfusion index (PI) and haemoglobin (Hb) concentration on accuracy were assessed by regression analysis.Results: Forty arterial blood samples paired with SpO2 and blood pressure measurements were obtained. SpO2 ranged from 42 ' 99 % and SaO2 from 43.7 ' 99.9%. MAP ranged from 24 24 ' 82 mmHg, PI from 0.1 ' 1.56 and Hb concentration from 71 - 114 g L-1. Masimo pulse oximetry measurements tended to underestimate oxyhaemoglobin saturation compared to co-oximetry with a bias (mean difference) of -2% and precision (standard deviation of the differences) of 6%. Accuracy appeared to decrease when SpO2 was less than 75%, however numbers were too small for statistical comparisons. Hb concentration and PI had no significant effect on accuracy, whereas MAP was negatively correlated with SpO2 bias.Conclusions: and clinical relevance Masimo SET pulse oximetry can provide reliable and continuous monitoring of oxyhaemoglobin saturation in anaesthetized pregnant sheep during clinically relevant levels of cardiopulmonary dysfunction. Further work is needed to assess pulse oximeter function during extreme hypotension and hypoxaemia.

AB - Objective: Evaluation of the accuracy of Masimo Signal Extraction Technology (SET) pulse oximetry in anaesthetized late gestational pregnant sheep.Study Design: Prospective experimental study.Animals: 17 pregnant merino ewes.Methods: Animals included in study were late gestation ewes undergoing general anaesthesia for caesarean delivery or foetal surgery in a medical research laboratory. Masimo Radical-7 pulse oximetry (SpO2) measurements were compared to co-oximetry (SaO2) measurements from arterial blood gas analyses. The failure rate of the pulse oximeter was calculated. Accuracy was assessed by Bland and Altman's (2007) limits of agreement method. The effect of mean arterial blood pressure (MAP), perfusion index (PI) and haemoglobin (Hb) concentration on accuracy were assessed by regression analysis.Results: Forty arterial blood samples paired with SpO2 and blood pressure measurements were obtained. SpO2 ranged from 42 ' 99 % and SaO2 from 43.7 ' 99.9%. MAP ranged from 24 24 ' 82 mmHg, PI from 0.1 ' 1.56 and Hb concentration from 71 - 114 g L-1. Masimo pulse oximetry measurements tended to underestimate oxyhaemoglobin saturation compared to co-oximetry with a bias (mean difference) of -2% and precision (standard deviation of the differences) of 6%. Accuracy appeared to decrease when SpO2 was less than 75%, however numbers were too small for statistical comparisons. Hb concentration and PI had no significant effect on accuracy, whereas MAP was negatively correlated with SpO2 bias.Conclusions: and clinical relevance Masimo SET pulse oximetry can provide reliable and continuous monitoring of oxyhaemoglobin saturation in anaesthetized pregnant sheep during clinically relevant levels of cardiopulmonary dysfunction. Further work is needed to assess pulse oximeter function during extreme hypotension and hypoxaemia.

KW - Anaesthesia

KW - Pregnancy

KW - Pulse oximetry

KW - Sheep

U2 - 10.1111/j.1467-2995.2012.00772.x

DO - 10.1111/j.1467-2995.2012.00772.x

M3 - Article

C2 - 22978823

VL - 40

SP - 149

EP - 156

JO - Veterinary Anaesthesia and Analgesia

JF - Veterinary Anaesthesia and Analgesia

SN - 1351-6574

IS - 2

ER -