First detection of plasmid-mediated colistin-resistance gene (mcr-1, mcr-2 and mcr-3) in Escherichia coli isolated from breeder poultry of Bangladesh

M.S. Jalal, A. Dutta, Tridip Das, M.Z. Islam

Research output: Other contribution to conferenceAbstractpeer-review

2 Downloads (Pure)

Abstract

Background: The Emergence of plasmid-mediated colistin resistance in poultry origin Escherichia coli has become a major global concern. As colistin has also been being used in breeder chicken for several years, we conducted this study in 108 breeder farms of Bangladesh to unveil the present prevalence and molecular basis of colistin-resistance of E. coli (CREC) in breeder poultry.
Methods and materials: During a one year study period, following standard wet-lab procedure, we isolated 24 (26.1%; 95%CI: 18.2–35.9) CREC among which 62.5% (95%CI: 38.5–81.6) isolates were confirmed, by both simplex and multiplex polymerase chain reaction (PCR), carrying one or more mcr gene(s).
Results: In PCR, the mcr-1, mcr-2 and mcr-3 were detected in eight (50%; 95%CI: 28–72). one (6.25%; 95%CI: Conclusion: As per our knowledge, it is the first report on the detection and sequencing of mcr-1 gene of E. coli isolated from breeder chicken. The findings of this study clarify the emergence of CREC in breeder chicken; and recommend the reduction of colistin usage along with adoption of an on-time surveillance system in poultry farms.
Original languageEnglish
Pages17-17
Number of pages1
DOIs
Publication statusPublished - 16 Nov 2020
Event19th International Congress on Infectious Diseases - Kuala Lumpur Convention Centre , Kuala Lumpur , Malaysia
Duration: 20 Feb 202023 Feb 2020

Conference

Conference19th International Congress on Infectious Diseases
Country/TerritoryMalaysia
CityKuala Lumpur
Period20/02/2023/02/20

Fingerprint

Dive into the research topics of 'First detection of plasmid-mediated colistin-resistance gene (mcr-1, mcr-2 and mcr-3) in Escherichia coli isolated from breeder poultry of Bangladesh'. Together they form a unique fingerprint.

Cite this