Genetic characterization of equine adenovirus type 1

Heather Cavanagh; Timothy J. Mahony; Thirumahal Vanniasinkam

doi:10.1016/j.vetmic.2011.08.014

Genetic characterization of equine adenovirus type 1

Heather Cavanagh, Timothy J. Mahony, Thirumahal Vanniasinkam

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Abstract

Two known serotypes of equine adenovirus (EAdV), equine adenovirus type 1 (EAdV-1) and equine adenovirus type 2 (EAdV-2) have been isolated from horses. EAdV-1 is predominantly associated with upper respiratory tract infections while EAdV-2 appears to be associated with gastrointestinal infections in horses. In this report the EAdV-1 genome has been sequenced for the first time. The EAdV-1 genome encoded genes are characteristic of the Mastadenovirus genus such as protein V and IX. Unexpectedly, phylogenetic reconstructions also revealed a close relationship between EAdV-1 and two recently characterized bat adenoviruses. The results of this study suggest that EAdV-1 may share a common ancestor with canine and bat adenoviruses.

Original language	English
Pages (from-to)	33-37
Number of pages	5
Journal	Veterinary Microbiology
Volume	155
Issue number	1
DOIs	https://doi.org/10.1016/j.vetmic.2011.08.014
Publication status	Published - Feb 2012

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title = "Genetic characterization of equine adenovirus type 1",

abstract = "Two known serotypes of equine adenovirus (EAdV), equine adenovirus type 1 (EAdV-1) and equine adenovirus type 2 (EAdV-2) have been isolated from horses. EAdV-1 is predominantly associated with upper respiratory tract infections while EAdV-2 appears to be associated with gastrointestinal infections in horses. In this report the EAdV-1 genome has been sequenced for the first time. The EAdV-1 genome encoded genes are characteristic of the Mastadenovirus genus such as protein V and IX. Unexpectedly, phylogenetic reconstructions also revealed a close relationship between EAdV-1 and two recently characterized bat adenoviruses. The results of this study suggest that EAdV-1 may share a common ancestor with canine and bat adenoviruses.",

keywords = "Equine adenovirus, Mastadenovirus, Phylogenetic analysis",

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AU - Cavanagh, Heather

AU - Mahony, Timothy J.

AU - Vanniasinkam, Thirumahal

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AB - Two known serotypes of equine adenovirus (EAdV), equine adenovirus type 1 (EAdV-1) and equine adenovirus type 2 (EAdV-2) have been isolated from horses. EAdV-1 is predominantly associated with upper respiratory tract infections while EAdV-2 appears to be associated with gastrointestinal infections in horses. In this report the EAdV-1 genome has been sequenced for the first time. The EAdV-1 genome encoded genes are characteristic of the Mastadenovirus genus such as protein V and IX. Unexpectedly, phylogenetic reconstructions also revealed a close relationship between EAdV-1 and two recently characterized bat adenoviruses. The results of this study suggest that EAdV-1 may share a common ancestor with canine and bat adenoviruses.

KW - Equine adenovirus

KW - Mastadenovirus

KW - Phylogenetic analysis

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DO - 10.1016/j.vetmic.2011.08.014

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JO - Veterinary Microbiology

JF - Veterinary Microbiology

IS - 1

ER -

Genetic characterization of equine adenovirus type 1

Abstract

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