Genoprotective effect of the Chinese herbal decoction Xiao Jian Zhong Tang

Y.-T. Szeto; N.-F. Cheng; Sokcheon Pak; Wouter Kalle

Genoprotective effect of the Chinese herbal decoction Xiao Jian Zhong Tang

Y.-T. Szeto
, N.-F. Cheng
, Sokcheon Pak
, Wouter Kalle

Hong Kong Institute of Vocational Education
Pamela Youde Nethersole Eastern Hospital, Hong Kong

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P

Original language	English
Pages (from-to)	389-392
Number of pages	4
Journal	Natural Product Communications
Volume	8
Issue number	3
Publication status	Published - 2013

Cite this

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title = "Genoprotective effect of the Chinese herbal decoction Xiao Jian Zhong Tang",

abstract = "The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P ",

keywords = "Antioxidant, Comet assay, DNA damage, Xiao Jian Zhong Tang",

author = "Y.-T. Szeto and N.-F. Cheng and Sokcheon Pak and Wouter Kalle",

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T1 - Genoprotective effect of the Chinese herbal decoction Xiao Jian Zhong Tang

AU - Szeto, Y.-T.

AU - Cheng, N.-F.

AU - Pak, Sokcheon

AU - Kalle, Wouter

N1 - Includes bibliographical references

PY - 2013

Y1 - 2013

N2 - The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P

AB - The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P

KW - Antioxidant

KW - Comet assay

KW - DNA damage

KW - Xiao Jian Zhong Tang

M3 - Article

SN - 1934-578X

VL - 8

SP - 389

EP - 392

JO - Natural Product Communications

JF - Natural Product Communications

IS - 3

ER -

Genoprotective effect of the Chinese herbal decoction Xiao Jian Zhong Tang

Abstract

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