Global, regional, and national incidence of six major immune-mediated inflammatory diseases: Findings from the global burden of disease study 2019

GBD 2019 IMID Collaborators; Dongze Wu; Yingzhao Jin; Yuhan Xing; Melsew Dagne Abate; Mohammadreza Abbasian; Mohsen Abbasi-Kangevari; Zeinab Abbasi-Kangevari; Foad Abd-Allah; Michael Abdelmasseh; Mohammad Amin Abdollahifar; Deldar Morad Abdulah; Aidin Abedi; Vida Abedi; Hassan Abidi; Richard Gyan Aboagye; Hassan Abolhassani; Katrina Abuabara; Morteza Abyadeh; Isaac Yeboah Addo; Kayode Nelson Adeniji; Abiola Victor Adepoju; Miracle Ayomikun Adesina; Qorinah Estiningtyas Sakilah Adnani; Mohsen Afarideh; Shahin Aghamiri; Antonella Agodi; Anurag Agrawal; Constanza Elizabeth Aguilera Arriagada; Aqeel Ahmad; Danish Ahmad; Sajjad Ahmad; Sohail Ahmad; Ali Ahmadi; Ali Ahmed; Ayman Ahmed; Janardhana P. Aithala; Abdullateef Abiodun Ajadi; Marjan Ajami; Mostafa Akbarzadeh-Khiavi; Fares Alahdab; Mohammad T. AlBataineh; Sharifullah Alemi; Adel Ali Saeed Al-Gheethi; Liaqat Ali; Sheikh Mohammad Alif; Joseph Uy Almazan; Sami Almustanyir; Jaber S. Alqahtani; Ibrahim Alqasmi; Ihsan Ullah Khan Altaf; Nelson Alvis-Guzman; Nelson J. Alvis-Zakzuk; Yaser Mohammed Al-Worafi; Hany Aly; Reza Amani; Hubert Amu; Ganiyu Adeniyi Amusa; Catalina Liliana Andrei; Adnan Ansar; Hossein Ansariniya; Anayochukwu Edward Anyasodor; Jalal Arabloo; Reza Arefnezhad; Judie Arulappan; Mohammad Asghari-Jafarabadi; Tahira Ashraf; Jamila Abdulhamid Atata; Seyyed Shamsadin Athari; Daniel Atlaw; Maha Moh d.Wahbi Atout; Avinash Aujayeb; Asma Tahir Awan; Haleh Ayatollahi; Sina Azadnajafabad; Ahmed Y. Azzam; Alaa Badawi; Ashish D. Badiye; Sara Bagherieh; Atif Amin Baig; Berihun Bantie Bantie; Martina Barchitta; Mainak Bardhan; Suzanne Lyn Barker-Collo; Francesco Barone-Adesi; Kavita Batra; Nebiyou Simegnew Bayileyegn; Amir Hossein Behnoush; Uzma Iqbal Belgaumi; Maryam Bemanalizadeh; Isabela M. Bensenor; Kebede A. Beyene; Akshaya Srikanth Bhagavathula; Pankaj Bhardwaj; Sonu Bhaskar; Ajay Nagesh Bhat; Saeid Bitaraf; Veera R. Bitra; Archith Boloor; Kaustubh Bora; João Silva Botelho; Rachelle Buchbinder; Daniela Calina; Luis Alberto Cámera; Andre F. Carvalho; Jeffrey Shi Kai Chan; Vijay Kumar Chattu; Endeshaw Chekol Abebe; Fatemeh Chichagi; Sungchul Choi; Tzu Chieh Chou; Dinh Toi Chu; Kaleb Coberly; Vera Marisa Costa; Rosa A.S. Couto; Natália Cruz-Martins; Omid Dadras; Xiaochen Dai; Giovanni Damiani; Ana Maria Dascalu; Mohsen Dashti; Sisay Abebe Debela; Robert Paul Dellavalle; Andreas K. Demetriades; Alemayehu Anley Demlash; Xinlei Deng; Hardik Dineshbhai Desai; Rupak Desai; Syed Masudur Rahman Dewan; Sourav Dey; Samath Dhamminda Dharmaratne; Daniel Diaz; Mahmoud Dibas; Ricardo Jorge Dinis-Oliveira; Mengistie Diress; Thanh Chi Do; Duy Khanh Doan; Masoud Dodangeh; Milad Dodangeh; Deepa Dongarwar; John Dube; Arkadiusz Marian Dziedzic; Abdelaziz Ed-Dra; Hisham Atan Edinur; Negin Eissazade; Michael Ekholuenetale; Temitope Cyrus Ekundayo; Noha Mousaad Elemam; Muhammed Elhadi; Ahmed O. Elmehrath; Omar Abdelsadek Abdou Elmeligy; Mehdi Emamverdi; Theophilus I. Emeto; Hawi Leul Esayas; Habitu Birhan Eshetu; Farshid Etaee; Adeniyi Francis Fagbamigbe; Shahriar Faghani; Ildar Ravisovich Fakhradiyev; Ali Fatehizadeh; Mobina Fathi; Alireza Feizkhah; Ginenus Fekadu; Mohammad Fereidouni; Seyed Mohammad Fereshtehnejad; João C. Fernandes; Pietro Ferrara; Getahun Fetensa; Irina Filip; Florian Fischer; Behzad Foroutan; Masoud Foroutan; Takeshi Fukumoto; Balasankar Ganesan; Belete Negese Belete Gemeda; Seyyed Hadi Ghamari; Mohammad Reza Ghasemi; Maryam Gholamalizadeh; Tiffany K. Gill; Richard F. Gillum; Mohamad Goldust; Mahaveer Golechha; Pouya Goleij; Davide Golinelli; Houman Goudarzi; Shi Yang Guan; Yang Guo; Bhawna Gupta; Veer Bala Gupta; Vivek Kumar Gupta; Rasool Haddadi; Najah R. Hadi; Rabih Halwani; Shafiul Haque; Ikramul Hasan; Reza Hashempour; Amr Hassan; Treska S. Hassan; Sara Hassanzadeh; Mohammed Bheser Hassen; Johannes Haubold; Khezar Hayat; Golnaz Heidari; Mohammad Heidari; Reza Heidari-Soureshjani; Claudiu Herteliu; Kamran Hessami; Kamal Hezam; Yuta Hiraike; Ramesh Holla; Mohammad Salar Hosseini; Hong Han Huynh; Bing Fang Hwang; Segun Emmanuel Ibitoye; Irena M. Ilic; Milena D. Ilic; Arad Iranmehr; Farideh Iravanpour; Nahlah Elkudssiah Ismail; Masao Iwagami; Chidozie C.D. Iwu; Louis Jacob; Morteza Jafarinia; Abdollah Jafarzadeh; Kasra Jahankhani; Haitham Jahrami; Mihajlo Jakovljevic; Elham Jamshidi; Chinmay T. Jani; Manthan Dilipkumar Janodia; Sathish Kumar Jayapal; Shubha Jayaram; Jayakumar Jeganathan; Jost B. Jonas; Abel Joseph; Nitin Joseph; Charity Ehimwenma Joshua; K. Vaishali; Billingsley Kaambwa; Ali Kabir; Zubair Kabir; Vidya Kadashetti; Feroze Kaliyadan; Fatemeh Kalroozi; Vineet Kumar Kamal; Amit Kandel; Himal Kandel; Srikanta Kanungo; Jafar Karami; Ibraheem M. Karaye; Mohammad Ali Moni; Jing Sun

doi:10.1016/j.eclinm.2023.102193

Global, regional, and national incidence of six major immune-mediated inflammatory diseases: Findings from the global burden of disease study 2019

GBD 2019 IMID Collaborators, Dongze Wu, Yingzhao Jin, Yuhan Xing, Melsew Dagne Abate, Mohammadreza Abbasian, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Foad Abd-Allah, Michael Abdelmasseh, Mohammad Amin Abdollahifar, Deldar Morad Abdulah, Aidin Abedi, Vida Abedi, Hassan Abidi, Richard Gyan Aboagye, Hassan Abolhassani, Katrina Abuabara, Morteza Abyadeh, Isaac Yeboah AddoKayode Nelson Adeniji, Abiola Victor Adepoju, Miracle Ayomikun Adesina, Qorinah Estiningtyas Sakilah Adnani, Mohsen Afarideh, Shahin Aghamiri, Antonella Agodi, Anurag Agrawal, Constanza Elizabeth Aguilera Arriagada, Aqeel Ahmad, Danish Ahmad, Sajjad Ahmad, Sohail Ahmad, Ali Ahmadi, Ali Ahmed, Ayman Ahmed, Janardhana P. Aithala, Abdullateef Abiodun Ajadi, Marjan Ajami, Mostafa Akbarzadeh-Khiavi, Fares Alahdab, Mohammad T. AlBataineh, Sharifullah Alemi, Adel Ali Saeed Al-Gheethi, Liaqat Ali, Sheikh Mohammad Alif, Joseph Uy Almazan, Sami Almustanyir, Jaber S. Alqahtani, Ibrahim Alqasmi, Ihsan Ullah Khan Altaf, Nelson Alvis-Guzman, Nelson J. Alvis-Zakzuk, Yaser Mohammed Al-Worafi, Hany Aly, Reza Amani, Hubert Amu, Ganiyu Adeniyi Amusa, Catalina Liliana Andrei, Adnan Ansar, Hossein Ansariniya, Anayochukwu Edward Anyasodor, Jalal Arabloo, Reza Arefnezhad, Judie Arulappan, Mohammad Asghari-Jafarabadi, Tahira Ashraf, Jamila Abdulhamid Atata, Seyyed Shamsadin Athari, Daniel Atlaw, Maha Moh d.Wahbi Atout, Avinash Aujayeb, Asma Tahir Awan, Haleh Ayatollahi, Sina Azadnajafabad, Ahmed Y. Azzam, Alaa Badawi, Ashish D. Badiye, Sara Bagherieh, Atif Amin Baig, Berihun Bantie Bantie, Martina Barchitta, Mainak Bardhan, Suzanne Lyn Barker-Collo, Francesco Barone-Adesi, Kavita Batra, Nebiyou Simegnew Bayileyegn, Amir Hossein Behnoush, Uzma Iqbal Belgaumi, Maryam Bemanalizadeh, Isabela M. Bensenor, Kebede A. Beyene, Akshaya Srikanth Bhagavathula, Pankaj Bhardwaj, Sonu Bhaskar, Ajay Nagesh Bhat, Saeid Bitaraf, Veera R. Bitra, Archith Boloor, Kaustubh Bora, João Silva Botelho, Rachelle Buchbinder, Daniela Calina, Luis Alberto Cámera, Andre F. Carvalho, Jeffrey Shi Kai Chan, Vijay Kumar Chattu, Endeshaw Chekol Abebe, Fatemeh Chichagi, Sungchul Choi, Tzu Chieh Chou, Dinh Toi Chu, Kaleb Coberly, Vera Marisa Costa, Rosa A.S. Couto, Natália Cruz-Martins, Omid Dadras, Xiaochen Dai, Giovanni Damiani, Ana Maria Dascalu, Mohsen Dashti, Sisay Abebe Debela, Robert Paul Dellavalle, Andreas K. Demetriades, Alemayehu Anley Demlash, Xinlei Deng, Hardik Dineshbhai Desai, Rupak Desai, Syed Masudur Rahman Dewan, Sourav Dey, Samath Dhamminda Dharmaratne, Daniel Diaz, Mahmoud Dibas, Ricardo Jorge Dinis-Oliveira, Mengistie Diress, Thanh Chi Do, Duy Khanh Doan, Masoud Dodangeh, Milad Dodangeh, Deepa Dongarwar, John Dube, Arkadiusz Marian Dziedzic, Abdelaziz Ed-Dra, Hisham Atan Edinur, Negin Eissazade, Michael Ekholuenetale, Temitope Cyrus Ekundayo, Noha Mousaad Elemam, Muhammed Elhadi, Ahmed O. Elmehrath, Omar Abdelsadek Abdou Elmeligy, Mehdi Emamverdi, Theophilus I. Emeto, Hawi Leul Esayas, Habitu Birhan Eshetu, Farshid Etaee, Adeniyi Francis Fagbamigbe, Shahriar Faghani, Ildar Ravisovich Fakhradiyev, Ali Fatehizadeh, Mobina Fathi, Alireza Feizkhah, Ginenus Fekadu, Mohammad Fereidouni, Seyed Mohammad Fereshtehnejad, João C. Fernandes, Pietro Ferrara, Getahun Fetensa, Irina Filip, Florian Fischer, Behzad Foroutan, Masoud Foroutan, Takeshi Fukumoto, Balasankar Ganesan, Belete Negese Belete Gemeda, Seyyed Hadi Ghamari, Mohammad Reza Ghasemi, Maryam Gholamalizadeh, Tiffany K. Gill, Richard F. Gillum, Mohamad Goldust, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Houman Goudarzi, Shi Yang Guan, Yang Guo, Bhawna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Rasool Haddadi, Najah R. Hadi, Rabih Halwani, Shafiul Haque, Ikramul Hasan, Reza Hashempour, Amr Hassan, Treska S. Hassan, Sara Hassanzadeh, Mohammed Bheser Hassen, Johannes Haubold, Khezar Hayat, Golnaz Heidari, Mohammad Heidari, Reza Heidari-Soureshjani, Claudiu Herteliu, Kamran Hessami, Kamal Hezam, Yuta Hiraike, Ramesh Holla, Mohammad Salar Hosseini, Hong Han Huynh, Bing Fang Hwang, Segun Emmanuel Ibitoye, Irena M. Ilic, Milena D. Ilic, Arad Iranmehr, Farideh Iravanpour, Nahlah Elkudssiah Ismail, Masao Iwagami, Chidozie C.D. Iwu, Louis Jacob, Morteza Jafarinia, Abdollah Jafarzadeh, Kasra Jahankhani, Haitham Jahrami, Mihajlo Jakovljevic, Elham Jamshidi, Chinmay T. Jani, Manthan Dilipkumar Janodia, Sathish Kumar Jayapal, Shubha Jayaram, Jayakumar Jeganathan, Jost B. Jonas, Abel Joseph, Nitin Joseph, Charity Ehimwenma Joshua, K. Vaishali, Billingsley Kaambwa, Ali Kabir, Zubair Kabir, Vidya Kadashetti, Feroze Kaliyadan, Fatemeh Kalroozi, Vineet Kumar Kamal, Amit Kandel, Himal Kandel, Srikanta Kanungo, Jafar Karami, Ibraheem M. Karaye, Mohammad Ali Moni, Jing Sun

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Abstract

BACKGROUND: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019.

METHODS: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends.

FINDINGS: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of -0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = -0.41), inflammatory bowel disease (AAPC = -0.72), multiple sclerosis (AAPC = -0.26), psoriasis (AAPC = -0.77), and atopic dermatitis (AAPC = -0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR.

INTERPRETATION: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively.

FUNDING: The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (2022QN38).

Original language	English
Article number	102193
Pages (from-to)	1-23
Number of pages	23
Journal	eClinicalMedicine
Volume	64
DOIs	https://doi.org/10.1016/j.eclinm.2023.102193
Publication status	Published - Oct 2023

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Cite this

GBD 2019 IMID Collaborators, Wu, D., Jin, Y., Xing, Y., Abate, M. D., Abbasian, M., Abbasi-Kangevari, M., Abbasi-Kangevari, Z., Abd-Allah, F., Abdelmasseh, M., Abdollahifar, M. A., Abdulah, D. M., Abedi, A., Abedi, V., Abidi, H., Aboagye, R. G., Abolhassani, H., Abuabara, K., Abyadeh, M., ... Sun, J. (2023). Global, regional, and national incidence of six major immune-mediated inflammatory diseases: Findings from the global burden of disease study 2019. eClinicalMedicine, 64, 1-23. Article 102193. https://doi.org/10.1016/j.eclinm.2023.102193

@article{1e304089de2a4e63b9d80bb671e24545,

title = "Global, regional, and national incidence of six major immune-mediated inflammatory diseases: Findings from the global burden of disease study 2019",

abstract = "BACKGROUND: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019.METHODS: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends.FINDINGS: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of -0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = -0.41), inflammatory bowel disease (AAPC = -0.72), multiple sclerosis (AAPC = -0.26), psoriasis (AAPC = -0.77), and atopic dermatitis (AAPC = -0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR.INTERPRETATION: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively.FUNDING: The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (2022QN38).",

keywords = "Global burden of disease study, Immune-mediated inflammatory disease, Incidence, Trend",

author = "{GBD 2019 IMID Collaborators} and Dongze Wu and Yingzhao Jin and Yuhan Xing and Abate, {Melsew Dagne} and Mohammadreza Abbasian and Mohsen Abbasi-Kangevari and Zeinab Abbasi-Kangevari and Foad Abd-Allah and Michael Abdelmasseh and Abdollahifar, {Mohammad Amin} and Abdulah, {Deldar Morad} and Aidin Abedi and Vida Abedi and Hassan Abidi and Aboagye, {Richard Gyan} and Hassan Abolhassani and Katrina Abuabara and Morteza Abyadeh and Addo, {Isaac Yeboah} and Adeniji, {Kayode Nelson} and Adepoju, {Abiola Victor} and Adesina, {Miracle Ayomikun} and Adnani, {Qorinah Estiningtyas Sakilah} and Mohsen Afarideh and Shahin Aghamiri and Antonella Agodi and Anurag Agrawal and Arriagada, {Constanza Elizabeth Aguilera} and Aqeel Ahmad and Danish Ahmad and Sajjad Ahmad and Sohail Ahmad and Ali Ahmadi and Ali Ahmed and Ayman Ahmed and Aithala, {Janardhana P.} and Ajadi, {Abdullateef Abiodun} and Marjan Ajami and Mostafa Akbarzadeh-Khiavi and Fares Alahdab and AlBataineh, {Mohammad T.} and Sharifullah Alemi and Al-Gheethi, {Adel Ali Saeed} and Liaqat Ali and Alif, {Sheikh Mohammad} and Almazan, {Joseph Uy} and Sami Almustanyir and Alqahtani, {Jaber S.} and Ibrahim Alqasmi and Altaf, {Ihsan Ullah Khan} and Nelson Alvis-Guzman and Alvis-Zakzuk, {Nelson J.} and Al-Worafi, {Yaser Mohammed} and Hany Aly and Reza Amani and Hubert Amu and Amusa, {Ganiyu Adeniyi} and Andrei, {Catalina Liliana} and Adnan Ansar and Hossein Ansariniya and Anyasodor, {Anayochukwu Edward} and Jalal Arabloo and Reza Arefnezhad and Judie Arulappan and Mohammad Asghari-Jafarabadi and Tahira Ashraf and Atata, {Jamila Abdulhamid} and Athari, {Seyyed Shamsadin} and Daniel Atlaw and Atout, {Maha Moh d.Wahbi} and Avinash Aujayeb and Awan, {Asma Tahir} and Haleh Ayatollahi and Sina Azadnajafabad and Azzam, {Ahmed Y.} and Alaa Badawi and Badiye, {Ashish D.} and Sara Bagherieh and Baig, {Atif Amin} and Bantie, {Berihun Bantie} and Martina Barchitta and Mainak Bardhan and Barker-Collo, {Suzanne Lyn} and Francesco Barone-Adesi and Kavita Batra and Bayileyegn, {Nebiyou Simegnew} and Behnoush, {Amir Hossein} and Belgaumi, {Uzma Iqbal} and Maryam Bemanalizadeh and Bensenor, {Isabela M.} and Beyene, {Kebede A.} and Bhagavathula, {Akshaya Srikanth} and Pankaj Bhardwaj and Sonu Bhaskar and Bhat, {Ajay Nagesh} and Saeid Bitaraf and Bitra, {Veera R.} and Archith Boloor and Kaustubh Bora and Botelho, {Jo{\~a}o Silva} and Rachelle Buchbinder and Daniela Calina and C{\'a}mera, {Luis Alberto} and Carvalho, {Andre F.} and Chan, {Jeffrey Shi Kai} and Chattu, {Vijay Kumar} and Abebe, {Endeshaw Chekol} and Fatemeh Chichagi and Sungchul Choi and Chou, {Tzu Chieh} and Chu, {Dinh Toi} and Kaleb Coberly and Costa, {Vera Marisa} and Couto, {Rosa A.S.} and Nat{\'a}lia Cruz-Martins and Omid Dadras and Xiaochen Dai and Giovanni Damiani and Dascalu, {Ana Maria} and Mohsen Dashti and Debela, {Sisay Abebe} and Dellavalle, {Robert Paul} and Demetriades, {Andreas K.} and Demlash, {Alemayehu Anley} and Xinlei Deng and Desai, {Hardik Dineshbhai} and Rupak Desai and Dewan, {Syed Masudur Rahman} and Sourav Dey and Dharmaratne, {Samath Dhamminda} and Daniel Diaz and Mahmoud Dibas and Dinis-Oliveira, {Ricardo Jorge} and Mengistie Diress and Do, {Thanh Chi} and Doan, {Duy Khanh} and Masoud Dodangeh and Milad Dodangeh and Deepa Dongarwar and John Dube and Dziedzic, {Arkadiusz Marian} and Abdelaziz Ed-Dra and Edinur, {Hisham Atan} and Negin Eissazade and Michael Ekholuenetale and Ekundayo, {Temitope Cyrus} and Elemam, {Noha Mousaad} and Muhammed Elhadi and Elmehrath, {Ahmed O.} and Elmeligy, {Omar Abdelsadek Abdou} and Mehdi Emamverdi and Emeto, {Theophilus I.} and Esayas, {Hawi Leul} and Eshetu, {Habitu Birhan} and Farshid Etaee and Fagbamigbe, {Adeniyi Francis} and Shahriar Faghani and Fakhradiyev, {Ildar Ravisovich} and Ali Fatehizadeh and Mobina Fathi and Alireza Feizkhah and Ginenus Fekadu and Mohammad Fereidouni and Fereshtehnejad, {Seyed Mohammad} and Fernandes, {Jo{\~a}o C.} and Pietro Ferrara and Getahun Fetensa and Irina Filip and Florian Fischer and Behzad Foroutan and Masoud Foroutan and Takeshi Fukumoto and Balasankar Ganesan and Gemeda, {Belete Negese Belete} and Ghamari, {Seyyed Hadi} and Ghasemi, {Mohammad Reza} and Maryam Gholamalizadeh and Gill, {Tiffany K.} and Gillum, {Richard F.} and Mohamad Goldust and Mahaveer Golechha and Pouya Goleij and Davide Golinelli and Houman Goudarzi and Guan, {Shi Yang} and Yang Guo and Bhawna Gupta and Gupta, {Veer Bala} and Gupta, {Vivek Kumar} and Rasool Haddadi and Hadi, {Najah R.} and Rabih Halwani and Shafiul Haque and Ikramul Hasan and Reza Hashempour and Amr Hassan and Hassan, {Treska S.} and Sara Hassanzadeh and Hassen, {Mohammed Bheser} and Johannes Haubold and Khezar Hayat and Golnaz Heidari and Mohammad Heidari and Reza Heidari-Soureshjani and Claudiu Herteliu and Kamran Hessami and Kamal Hezam and Yuta Hiraike and Ramesh Holla and Hosseini, {Mohammad Salar} and Huynh, {Hong Han} and Hwang, {Bing Fang} and Ibitoye, {Segun Emmanuel} and Ilic, {Irena M.} and Ilic, {Milena D.} and Arad Iranmehr and Farideh Iravanpour and Ismail, {Nahlah Elkudssiah} and Masao Iwagami and Iwu, {Chidozie C.D.} and Louis Jacob and Morteza Jafarinia and Abdollah Jafarzadeh and Kasra Jahankhani and Haitham Jahrami and Mihajlo Jakovljevic and Elham Jamshidi and Jani, {Chinmay T.} and Janodia, {Manthan Dilipkumar} and Jayapal, {Sathish Kumar} and Shubha Jayaram and Jayakumar Jeganathan and Jonas, {Jost B.} and Abel Joseph and Nitin Joseph and Joshua, {Charity Ehimwenma} and K. Vaishali and Billingsley Kaambwa and Ali Kabir and Zubair Kabir and Vidya Kadashetti and Feroze Kaliyadan and Fatemeh Kalroozi and Kamal, {Vineet Kumar} and Amit Kandel and Himal Kandel and Srikanta Kanungo and Jafar Karami and Karaye, {Ibraheem M.} and Moni, {Mohammad Ali} and Jing Sun",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2023",

month = oct,

doi = "10.1016/j.eclinm.2023.102193",

language = "English",

volume = "64",

pages = "1--23",

journal = "eClinicalMedicine",

issn = "2589-5370",

publisher = "Lancet Publishing Group",

}

GBD 2019 IMID Collaborators, Wu, D, Jin, Y, Xing, Y, Abate, MD, Abbasian, M, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, Abd-Allah, F, Abdelmasseh, M, Abdollahifar, MA, Abdulah, DM, Abedi, A, Abedi, V, Abidi, H, Aboagye, RG, Abolhassani, H, Abuabara, K, Abyadeh, M, Addo, IY, Adeniji, KN, Adepoju, AV, Adesina, MA, Adnani, QES, Afarideh, M, Aghamiri, S, Agodi, A, Agrawal, A, Arriagada, CEA, Ahmad, A, Ahmad, D, Ahmad, S, Ahmad, S, Ahmadi, A, Ahmed, A, Ahmed, A, Aithala, JP, Ajadi, AA, Ajami, M, Akbarzadeh-Khiavi, M, Alahdab, F, AlBataineh, MT, Alemi, S, Al-Gheethi, AAS, Ali, L, Alif, SM, Almazan, JU, Almustanyir, S, Alqahtani, JS, Alqasmi, I, Altaf, IUK, Alvis-Guzman, N, Alvis-Zakzuk, NJ, Al-Worafi, YM, Aly, H, Amani, R, Amu, H, Amusa, GA, Andrei, CL, Ansar, A, Ansariniya, H, Anyasodor, AE, Arabloo, J, Arefnezhad, R, Arulappan, J, Asghari-Jafarabadi, M, Ashraf, T, Atata, JA, Athari, SS, Atlaw, D, Atout, MMDW, Aujayeb, A, Awan, AT, Ayatollahi, H, Azadnajafabad, S, Azzam, AY, Badawi, A, Badiye, AD, Bagherieh, S, Baig, AA, Bantie, BB, Barchitta, M, Bardhan, M, Barker-Collo, SL, Barone-Adesi, F, Batra, K, Bayileyegn, NS, Behnoush, AH, Belgaumi, UI, Bemanalizadeh, M, Bensenor, IM, Beyene, KA, Bhagavathula, AS, Bhardwaj, P, Bhaskar, S, Bhat, AN, Bitaraf, S, Bitra, VR, Boloor, A, Bora, K, Botelho, JS, Buchbinder, R, Calina, D, Cámera, LA, Carvalho, AF, Chan, JSK, Chattu, VK, Abebe, EC, Chichagi, F, Choi, S, Chou, TC, Chu, DT, Coberly, K, Costa, VM, Couto, RAS, Cruz-Martins, N, Dadras, O, Dai, X, Damiani, G, Dascalu, AM, Dashti, M, Debela, SA, Dellavalle, RP, Demetriades, AK, Demlash, AA, Deng, X, Desai, HD, Desai, R, Dewan, SMR, Dey, S, Dharmaratne, SD, Diaz, D, Dibas, M, Dinis-Oliveira, RJ, Diress, M, Do, TC, Doan, DK, Dodangeh, M, Dodangeh, M, Dongarwar, D, Dube, J, Dziedzic, AM, Ed-Dra, A, Edinur, HA, Eissazade, N, Ekholuenetale, M, Ekundayo, TC, Elemam, NM, Elhadi, M, Elmehrath, AO, Elmeligy, OAA, Emamverdi, M, Emeto, TI, Esayas, HL, Eshetu, HB, Etaee, F, Fagbamigbe, AF, Faghani, S, Fakhradiyev, IR, Fatehizadeh, A, Fathi, M, Feizkhah, A, Fekadu, G, Fereidouni, M, Fereshtehnejad, SM, Fernandes, JC, Ferrara, P, Fetensa, G, Filip, I, Fischer, F, Foroutan, B, Foroutan, M, Fukumoto, T, Ganesan, B, Gemeda, BNB, Ghamari, SH, Ghasemi, MR, Gholamalizadeh, M, Gill, TK, Gillum, RF, Goldust, M, Golechha, M, Goleij, P, Golinelli, D, Goudarzi, H, Guan, SY, Guo, Y, Gupta, B, Gupta, VB, Gupta, VK, Haddadi, R, Hadi, NR, Halwani, R, Haque, S, Hasan, I, Hashempour, R, Hassan, A, Hassan, TS, Hassanzadeh, S, Hassen, MB, Haubold, J, Hayat, K, Heidari, G, Heidari, M, Heidari-Soureshjani, R, Herteliu, C, Hessami, K, Hezam, K, Hiraike, Y, Holla, R, Hosseini, MS, Huynh, HH, Hwang, BF, Ibitoye, SE, Ilic, IM, Ilic, MD, Iranmehr, A, Iravanpour, F, Ismail, NE, Iwagami, M, Iwu, CCD, Jacob, L, Jafarinia, M, Jafarzadeh, A, Jahankhani, K, Jahrami, H, Jakovljevic, M, Jamshidi, E, Jani, CT, Janodia, MD, Jayapal, SK, Jayaram, S, Jeganathan, J, Jonas, JB, Joseph, A, Joseph, N, Joshua, CE, Vaishali, K, Kaambwa, B, Kabir, A, Kabir, Z, Kadashetti, V, Kaliyadan, F, Kalroozi, F, Kamal, VK, Kandel, A, Kandel, H, Kanungo, S, Karami, J, Karaye, IM, Moni, MA & Sun, J 2023, 'Global, regional, and national incidence of six major immune-mediated inflammatory diseases: Findings from the global burden of disease study 2019', eClinicalMedicine, vol. 64, 102193, pp. 1-23. https://doi.org/10.1016/j.eclinm.2023.102193

TY - JOUR

T1 - Global, regional, and national incidence of six major immune-mediated inflammatory diseases

T2 - Findings from the global burden of disease study 2019

AU - GBD 2019 IMID Collaborators

AU - Wu, Dongze

AU - Jin, Yingzhao

AU - Xing, Yuhan

AU - Abate, Melsew Dagne

AU - Abbasian, Mohammadreza

AU - Abbasi-Kangevari, Mohsen

AU - Abbasi-Kangevari, Zeinab

AU - Abd-Allah, Foad

AU - Abdelmasseh, Michael

AU - Abdollahifar, Mohammad Amin

AU - Abdulah, Deldar Morad

AU - Abedi, Aidin

AU - Abedi, Vida

AU - Abidi, Hassan

AU - Aboagye, Richard Gyan

AU - Abolhassani, Hassan

AU - Abuabara, Katrina

AU - Abyadeh, Morteza

AU - Addo, Isaac Yeboah

AU - Adeniji, Kayode Nelson

AU - Adepoju, Abiola Victor

AU - Adesina, Miracle Ayomikun

AU - Adnani, Qorinah Estiningtyas Sakilah

AU - Afarideh, Mohsen

AU - Aghamiri, Shahin

AU - Agodi, Antonella

AU - Agrawal, Anurag

AU - Arriagada, Constanza Elizabeth Aguilera

AU - Ahmad, Aqeel

AU - Ahmad, Danish

AU - Ahmad, Sajjad

AU - Ahmad, Sohail

AU - Ahmadi, Ali

AU - Ahmed, Ali

AU - Ahmed, Ayman

AU - Aithala, Janardhana P.

AU - Ajadi, Abdullateef Abiodun

AU - Ajami, Marjan

AU - Akbarzadeh-Khiavi, Mostafa

AU - Alahdab, Fares

AU - AlBataineh, Mohammad T.

AU - Alemi, Sharifullah

AU - Al-Gheethi, Adel Ali Saeed

AU - Ali, Liaqat

AU - Alif, Sheikh Mohammad

AU - Almazan, Joseph Uy

AU - Almustanyir, Sami

AU - Alqahtani, Jaber S.

AU - Alqasmi, Ibrahim

AU - Altaf, Ihsan Ullah Khan

AU - Alvis-Guzman, Nelson

AU - Alvis-Zakzuk, Nelson J.

AU - Al-Worafi, Yaser Mohammed

AU - Aly, Hany

AU - Amani, Reza

AU - Amu, Hubert

AU - Amusa, Ganiyu Adeniyi

AU - Andrei, Catalina Liliana

AU - Ansar, Adnan

AU - Ansariniya, Hossein

AU - Anyasodor, Anayochukwu Edward

AU - Arabloo, Jalal

AU - Arefnezhad, Reza

AU - Arulappan, Judie

AU - Asghari-Jafarabadi, Mohammad

AU - Ashraf, Tahira

AU - Atata, Jamila Abdulhamid

AU - Athari, Seyyed Shamsadin

AU - Atlaw, Daniel

AU - Atout, Maha Moh d.Wahbi

AU - Aujayeb, Avinash

AU - Awan, Asma Tahir

AU - Ayatollahi, Haleh

AU - Azadnajafabad, Sina

AU - Azzam, Ahmed Y.

AU - Badawi, Alaa

AU - Badiye, Ashish D.

AU - Bagherieh, Sara

AU - Baig, Atif Amin

AU - Bantie, Berihun Bantie

AU - Barchitta, Martina

AU - Bardhan, Mainak

AU - Barker-Collo, Suzanne Lyn

AU - Barone-Adesi, Francesco

AU - Batra, Kavita

AU - Bayileyegn, Nebiyou Simegnew

AU - Behnoush, Amir Hossein

AU - Belgaumi, Uzma Iqbal

AU - Bemanalizadeh, Maryam

AU - Bensenor, Isabela M.

AU - Beyene, Kebede A.

AU - Bhagavathula, Akshaya Srikanth

AU - Bhardwaj, Pankaj

AU - Bhaskar, Sonu

AU - Bhat, Ajay Nagesh

AU - Bitaraf, Saeid

AU - Bitra, Veera R.

AU - Boloor, Archith

AU - Bora, Kaustubh

AU - Botelho, João Silva

AU - Buchbinder, Rachelle

AU - Calina, Daniela

AU - Cámera, Luis Alberto

AU - Carvalho, Andre F.

AU - Chan, Jeffrey Shi Kai

AU - Chattu, Vijay Kumar

AU - Abebe, Endeshaw Chekol

AU - Chichagi, Fatemeh

AU - Choi, Sungchul

AU - Chou, Tzu Chieh

AU - Chu, Dinh Toi

AU - Coberly, Kaleb

AU - Costa, Vera Marisa

AU - Couto, Rosa A.S.

AU - Cruz-Martins, Natália

AU - Dadras, Omid

AU - Dai, Xiaochen

AU - Damiani, Giovanni

AU - Dascalu, Ana Maria

AU - Dashti, Mohsen

AU - Debela, Sisay Abebe

AU - Dellavalle, Robert Paul

AU - Demetriades, Andreas K.

AU - Demlash, Alemayehu Anley

AU - Deng, Xinlei

AU - Desai, Hardik Dineshbhai

AU - Desai, Rupak

AU - Dewan, Syed Masudur Rahman

AU - Dey, Sourav

AU - Dharmaratne, Samath Dhamminda

AU - Diaz, Daniel

AU - Dibas, Mahmoud

AU - Dinis-Oliveira, Ricardo Jorge

AU - Diress, Mengistie

AU - Do, Thanh Chi

AU - Doan, Duy Khanh

AU - Dodangeh, Masoud

AU - Dodangeh, Milad

AU - Dongarwar, Deepa

AU - Dube, John

AU - Dziedzic, Arkadiusz Marian

AU - Ed-Dra, Abdelaziz

AU - Edinur, Hisham Atan

AU - Eissazade, Negin

AU - Ekholuenetale, Michael

AU - Ekundayo, Temitope Cyrus

AU - Elemam, Noha Mousaad

AU - Elhadi, Muhammed

AU - Elmehrath, Ahmed O.

AU - Elmeligy, Omar Abdelsadek Abdou

AU - Emamverdi, Mehdi

AU - Emeto, Theophilus I.

AU - Esayas, Hawi Leul

AU - Eshetu, Habitu Birhan

AU - Etaee, Farshid

AU - Fagbamigbe, Adeniyi Francis

AU - Faghani, Shahriar

AU - Fakhradiyev, Ildar Ravisovich

AU - Fatehizadeh, Ali

AU - Fathi, Mobina

AU - Feizkhah, Alireza

AU - Fekadu, Ginenus

AU - Fereidouni, Mohammad

AU - Fereshtehnejad, Seyed Mohammad

AU - Fernandes, João C.

AU - Ferrara, Pietro

AU - Fetensa, Getahun

AU - Filip, Irina

AU - Fischer, Florian

AU - Foroutan, Behzad

AU - Foroutan, Masoud

AU - Fukumoto, Takeshi

AU - Ganesan, Balasankar

AU - Gemeda, Belete Negese Belete

AU - Ghamari, Seyyed Hadi

AU - Ghasemi, Mohammad Reza

AU - Gholamalizadeh, Maryam

AU - Gill, Tiffany K.

AU - Gillum, Richard F.

AU - Goldust, Mohamad

AU - Golechha, Mahaveer

AU - Goleij, Pouya

AU - Golinelli, Davide

AU - Goudarzi, Houman

AU - Guan, Shi Yang

AU - Guo, Yang

AU - Gupta, Bhawna

AU - Gupta, Veer Bala

AU - Gupta, Vivek Kumar

AU - Haddadi, Rasool

AU - Hadi, Najah R.

AU - Halwani, Rabih

AU - Haque, Shafiul

AU - Hasan, Ikramul

AU - Hashempour, Reza

AU - Hassan, Amr

AU - Hassan, Treska S.

AU - Hassanzadeh, Sara

AU - Hassen, Mohammed Bheser

AU - Haubold, Johannes

AU - Hayat, Khezar

AU - Heidari, Golnaz

AU - Heidari, Mohammad

AU - Heidari-Soureshjani, Reza

AU - Herteliu, Claudiu

AU - Hessami, Kamran

AU - Hezam, Kamal

AU - Hiraike, Yuta

AU - Holla, Ramesh

AU - Hosseini, Mohammad Salar

AU - Huynh, Hong Han

AU - Hwang, Bing Fang

AU - Ibitoye, Segun Emmanuel

AU - Ilic, Irena M.

AU - Ilic, Milena D.

AU - Iranmehr, Arad

AU - Iravanpour, Farideh

AU - Ismail, Nahlah Elkudssiah

AU - Iwagami, Masao

AU - Iwu, Chidozie C.D.

AU - Jacob, Louis

AU - Jafarinia, Morteza

AU - Jafarzadeh, Abdollah

AU - Jahankhani, Kasra

AU - Jahrami, Haitham

AU - Jakovljevic, Mihajlo

AU - Jamshidi, Elham

AU - Jani, Chinmay T.

AU - Janodia, Manthan Dilipkumar

AU - Jayapal, Sathish Kumar

AU - Jayaram, Shubha

AU - Jeganathan, Jayakumar

AU - Jonas, Jost B.

AU - Joseph, Abel

AU - Joseph, Nitin

AU - Joshua, Charity Ehimwenma

AU - Vaishali, K.

AU - Kaambwa, Billingsley

AU - Kabir, Ali

AU - Kabir, Zubair

AU - Kadashetti, Vidya

AU - Kaliyadan, Feroze

AU - Kalroozi, Fatemeh

AU - Kamal, Vineet Kumar

AU - Kandel, Amit

AU - Kandel, Himal

AU - Kanungo, Srikanta

AU - Karami, Jafar

AU - Karaye, Ibraheem M.

AU - Moni, Mohammad Ali

AU - Sun, Jing

PY - 2023/10

Y1 - 2023/10

N2 - BACKGROUND: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019.METHODS: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends.FINDINGS: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of -0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = -0.41), inflammatory bowel disease (AAPC = -0.72), multiple sclerosis (AAPC = -0.26), psoriasis (AAPC = -0.77), and atopic dermatitis (AAPC = -0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR.INTERPRETATION: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively.FUNDING: The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (2022QN38).

AB - BACKGROUND: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019.METHODS: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends.FINDINGS: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of -0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = -0.41), inflammatory bowel disease (AAPC = -0.72), multiple sclerosis (AAPC = -0.26), psoriasis (AAPC = -0.77), and atopic dermatitis (AAPC = -0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR.INTERPRETATION: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively.FUNDING: The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (2022QN38).

KW - Global burden of disease study

KW - Immune-mediated inflammatory disease

KW - Incidence

KW - Trend

UR - http://www.scopus.com/inward/record.url?scp=85172929794&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85172929794&partnerID=8YFLogxK

U2 - 10.1016/j.eclinm.2023.102193

DO - 10.1016/j.eclinm.2023.102193

M3 - Article

C2 - 37731935

AN - SCOPUS:85172929794

SN - 2589-5370

VL - 64

SP - 1

EP - 23

JO - eClinicalMedicine

JF - eClinicalMedicine

M1 - 102193

ER -

Global, regional, and national incidence of six major immune-mediated inflammatory diseases: Findings from the global burden of disease study 2019

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