Heart rate variability and QT dispersion in a cohort of diabetes patients.

Herbert Jelinek, Ahsan Habib Khandoker, Marimuthu Palaniswami, Simon McDonald

Research output: Book chapter/Published conference paperConference paperpeer-review

9 Citations (Scopus)
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Heart rate is dependent on a cycle of depolarization and repolarization of the atria and ventricles that is regulated by intrinsic and extrinsic factors. Inhomogeneity in ventricular repolarization, measured as QT interval dispersion (QTd) is likely to lead to arrhythmia. The role of the autonomic nervous system in the development of this inhomogeneity is still uncertain. Autonomic regulation can be measured using the tone-entropy algorithm, which indicates inter-beat interval variation.When a sliding cut-off for QTd was used only the control group had a significant association between QTd and both tone and entropy. This finding suggests that for certain levels of ventricular inhomogeneity, autonomic control becomes more dissociated from intra-beta variation measured by QTd. This may be an early sign of potentially fatal arrhythmia.
Original languageEnglish
Title of host publicationCinC 2010
Place of PublicationBelfast, Ireland
Number of pages4
ISBN (Electronic)9781424473182
Publication statusPublished - 2010
EventComputers in Cardiology - Belfast, UK, United Kingdom
Duration: 26 Sept 201029 Sept 2010


ConferenceComputers in Cardiology
Country/TerritoryUnited Kingdom


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