TY - JOUR
T1 - High Prevalence of Schistosoma japonicum and Fasciola gigantica in Bovines from Northern Samar, the Philippines
AU - Gordon, Catherine A.
AU - Acosta, Luz P.
AU - Gobert, Geoffrey N.
AU - Jiz, Mario
AU - Olveda, Remigio M.
AU - Ross, Allen G.
AU - Gray, Darren J.
AU - Williams, Gail M.
AU - Harn, Donald
AU - Li, Yuesheng
AU - McManus, Donald P.
N1 - Publisher Copyright:
© 2015 Gordon et al.
PY - 2015
Y1 - 2015
N2 - The cause of zoonotic schistosomiasis in the Philippines is Schistosoma japonicum,
which infects up to 46 mammalian hosts, including humans and bovines.
In China, water buffaloes have been identified as major reservoir hosts
for schistosomiasis japonica, contributing up to 75% of human
transmission. In the Philippines, water buffaloes (carabao; Bubalus bubalis carabanesis)
have, historically, been considered unimportant reservoirs. We
therefore revisited the possible role of bovines in schistosome
transmission in the Philippines, using the recently described
formalin-ethyl acetate sedimentation (FEA-SD) technique and a qPCR assay
to examine fecal samples from 153 bovines (both carabao and cattle)
from six barangays in Northern Samar. A high prevalence of S. japonicum
was found using qPCR and FEA-SD in both cattle (87.50% and 77.08%,
respectively) and carabao (80.00% and 55.24%, respectively). The average
daily egg output for each bovine was calculated at 195,000. High
prevalence and infection intensity of F. gigantica was also
found in the bovines by qPCR and FEA-SD (95.33% and 96.00%,
respectively). The identification of bovines as major reservoir hosts
for S. japonicum transmission suggests that bovine treatment
and/or vaccination, as one becomes available, should be included in any
future control program that aims to reduce the disease burden due to
schistosomiasis in the Philippines.
AB - The cause of zoonotic schistosomiasis in the Philippines is Schistosoma japonicum,
which infects up to 46 mammalian hosts, including humans and bovines.
In China, water buffaloes have been identified as major reservoir hosts
for schistosomiasis japonica, contributing up to 75% of human
transmission. In the Philippines, water buffaloes (carabao; Bubalus bubalis carabanesis)
have, historically, been considered unimportant reservoirs. We
therefore revisited the possible role of bovines in schistosome
transmission in the Philippines, using the recently described
formalin-ethyl acetate sedimentation (FEA-SD) technique and a qPCR assay
to examine fecal samples from 153 bovines (both carabao and cattle)
from six barangays in Northern Samar. A high prevalence of S. japonicum
was found using qPCR and FEA-SD in both cattle (87.50% and 77.08%,
respectively) and carabao (80.00% and 55.24%, respectively). The average
daily egg output for each bovine was calculated at 195,000. High
prevalence and infection intensity of F. gigantica was also
found in the bovines by qPCR and FEA-SD (95.33% and 96.00%,
respectively). The identification of bovines as major reservoir hosts
for S. japonicum transmission suggests that bovine treatment
and/or vaccination, as one becomes available, should be included in any
future control program that aims to reduce the disease burden due to
schistosomiasis in the Philippines.
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U2 - 10.1371/journal.pntd.0003108
DO - 10.1371/journal.pntd.0003108
M3 - Article
C2 - 25643317
AN - SCOPUS:84924078705
SN - 1935-2727
VL - 9
JO - PLoS Neglected Tropical Diseases
JF - PLoS Neglected Tropical Diseases
IS - 2
M1 - e0003108
ER -
