Hypochlorite-oxidised low-density lipoproteins in human atherosclerosis

Linda Hazell

Research output: ThesisDoctoral Thesis

Abstract

Damage to arterial walls contributes to atherosclerosis (thickening of the arteries) though the pivotal factors remain controversial. Hypochlorite/hypochlorous acid is a strong oxidant produced by white blood cells of the immune system. I discovered that hypochlorite causes types of damage potentially relevant to atherosclerosis and that such damage can be found in atherosclerotic lesions.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Sydney
Supervisors/Advisors
  • Stocker, Roland, Principal Supervisor, External person
Thesis sponsors
Publication statusPublished - 1997

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