AIM:This study aimed to investigate the impact of carotid artery stenting (CAS) on plasma levels of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-') and C-reactive protein (CRP).METHODS: The levels of CRP, IL-6, and TNF-' were measured in 61 patients before CAS, 1 h, 2 weeks, 1 month, 6 months, and 12 months after the stenting.RESULTS: The levels of CRP, IL-6 and TNF-' increased immediately after CAS (P<0.05 or <0.01). The levels of CRP, IL-6 and TNF-' in patients receiving two stents for multiple lesions or single diffusive lesions was also high than in patients receiving one stent for a single lesion (P<0.05 or <0.01). The levels of CRP, IL-6 and TNF-' in patients with restenosis (14/61, or 23%) were higher than in those without restenosis (P<0.05 or <0.01).CONCLUSION: CAS was associated with a significant increase in plasma CRP, IL-6 and TNF-'. The levels of these inflammatory factors in patients with post-CAS restenosis were higher than in those without restenosis.
|Number of pages||5|
|Journal||International Angiology: a journal on angiology|
|Publication status||Published - Feb 2012|
Xia, Z-Y. A., Yang, H., Qu, H-Q., Cheng, W. -D., & Wang, L. (2012). Impact of carotid artery stenting on plasma interleukin-6, tumor necrosis factor-' and C-reactive protein. International Angiology: a journal on angiology, 31(1), 28-32.