In Vitro Screening of Methanol Plant Extracts For Their Antibacterial Activity

Tariq Hussain, Muhammad Arshad, Khan Sarzamin, Hamid Sattar, Muhammad Qureshi

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)
7 Downloads (Pure)


The purpose of this study was to observe the antibacterial activity of aqueous methanolic extracts of 10 plants against 2-gram negative bacteria (Pasteurella multocida, Escherichia coli) and 3-gram positive bacteria (Bacillus cereus, Staphylococcus aureus, Corynebacterium bovis) by using disc diffusion method. The minimum inhibitory concentration (MIC) was determined by agar well diffusion method and agar dilution method. All the bacteria were susceptible to different plant extracts. Lawsonia inermis, Embellia ribes and Santalum album showed antibacterial activity against all the tested bacteria. The extract of Santalum album showed maximum antibacterial activity of the 10 plant extracts used. Bacillus cereus and Pasteurella multocida were the most sensitive bacteria against most of the plant extracts. It is clear from the results of the present studies that the plant extracts have great potential as antimicrobial compounds against bacteria. However, there is a need of further research to isolate the active ingredients for further pharmacological evaluation.
Original languageEnglish
Pages (from-to)531-538
Number of pages8
JournalPakistan Journal of Botany
Issue number1
Publication statusPublished - Feb 2011


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