Interactions between cannabis and schizophrenia in humans and rodents

Ahmed A. Moustafa; Mohamed Salama; Roseanne Peak; Richard Tindle; Amir Salem; Szabolcs Keri; Błazej Misiak; Dorota Frydecka; Wael Mohamed

doi:10.1515/revneuro-2016-0083

Interactions between cannabis and schizophrenia in humans and rodents

Ahmed A. Moustafa, Mohamed Salama, Roseanne Peak, Richard Tindle, Amir Salem, Szabolcs Keri, Błazej Misiak, Dorota Frydecka, Wael Mohamed

Psychology

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

In this review, we provide an overview of the relationship between cannabis use and the development of schizophrenia, using both animal and human studies. We further discuss the potential neural mechanism that may mediate the relationship between cannabis use and schizophrenia symptoms. We finally provide clinical implications and future studies that can further elucidate the relationship between cannabis and schizophrenia.

Original language	English
Pages (from-to)	811-823
Number of pages	13
Journal	Reviews in the Neurosciences
Volume	28
Issue number	7
Early online date	12 May 2017
DOIs	https://doi.org/10.1515/revneuro-2016-0083
Publication status	Published - 26 Oct 2017

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title = "Interactions between cannabis and schizophrenia in humans and rodents",

abstract = "In this review, we provide an overview of the relationship between cannabis use and the development of schizophrenia, using both animal and human studies. We further discuss the potential neural mechanism that may mediate the relationship between cannabis use and schizophrenia symptoms. We finally provide clinical implications and future studies that can further elucidate the relationship between cannabis and schizophrenia.",

keywords = "Cannabis, Endocannabinoid receptors, Negative symptoms, Positive symptoms, Schizophrenia",

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AU - Moustafa, Ahmed A.

AU - Salama, Mohamed

AU - Peak, Roseanne

AU - Tindle, Richard

AU - Salem, Amir

AU - Keri, Szabolcs

AU - Misiak, Błazej

AU - Frydecka, Dorota

AU - Mohamed, Wael

N1 - Includes bibliographical references.

PY - 2017/10/26

Y1 - 2017/10/26

N2 - In this review, we provide an overview of the relationship between cannabis use and the development of schizophrenia, using both animal and human studies. We further discuss the potential neural mechanism that may mediate the relationship between cannabis use and schizophrenia symptoms. We finally provide clinical implications and future studies that can further elucidate the relationship between cannabis and schizophrenia.

AB - In this review, we provide an overview of the relationship between cannabis use and the development of schizophrenia, using both animal and human studies. We further discuss the potential neural mechanism that may mediate the relationship between cannabis use and schizophrenia symptoms. We finally provide clinical implications and future studies that can further elucidate the relationship between cannabis and schizophrenia.

KW - Cannabis

KW - Endocannabinoid receptors

KW - Negative symptoms

KW - Positive symptoms

KW - Schizophrenia

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VL - 28

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JO - Reviews in the Neurosciences

JF - Reviews in the Neurosciences

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Interactions between cannabis and schizophrenia in humans and rodents

Abstract

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