Intercellular signaling between adipose tissue and muscle tissue

T. A. Kokta, M. V. Dodson, A. Gertler, R. A. Hill

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Adipose and muscle tissues undergo regulated growth and differentiation processes that are modulated by a wide range of factors. The interactions between myogenic cells and adipocytes play a significant role in growth and development, including the rate and extent of myogenesis, muscle growth, adipogenesis, lipogenesis/lipolysis, and in the utilization of energy substrates. Important hormones and growth factors involved in the regulation of these processes include glucocorticoids, insulin-like growth factors, various cytokines, insulin, and leptin. Interactions among these axes have important implications in their influence on relative fat and lean deposition and the efficiency of energy utilization in growth and development. As research progresses to better clarify the interactions among adipose tissue depots and muscle of different fiber types, pathways will become better understood, ultimately leading to the optimized management of fat and lean growth in domestic livestock species. This review will focus on elements of intercellular signaling, using data from cell culture studies to illustrate specific examples of signaling pathways between cells. (C) 2004 Elsevier Inc. All rights reserved.
Original languageEnglish
Pages (from-to)303-331
Number of pages29
JournalDomestic Animal Endocrinology
Volume27
Issue number4
DOIs
Publication statusPublished - 2004

Fingerprint

muscle tissues
adipose tissue
Adipose Tissue
growth and development
Growth and Development
Muscles
muscle development
lipogenesis
somatomedins
lipolysis
energy efficiency
lipids
Growth
glucocorticoids
leptin
adipocytes
Fats
muscle fibers
growth factors
Adipogenesis

Cite this

Kokta, T. A. ; Dodson, M. V. ; Gertler, A. ; Hill, R. A. / Intercellular signaling between adipose tissue and muscle tissue. In: Domestic Animal Endocrinology. 2004 ; Vol. 27, No. 4. pp. 303-331.
@article{34c9fe62b9974a1297eeeaceebc8ae2e,
title = "Intercellular signaling between adipose tissue and muscle tissue",
abstract = "Adipose and muscle tissues undergo regulated growth and differentiation processes that are modulated by a wide range of factors. The interactions between myogenic cells and adipocytes play a significant role in growth and development, including the rate and extent of myogenesis, muscle growth, adipogenesis, lipogenesis/lipolysis, and in the utilization of energy substrates. Important hormones and growth factors involved in the regulation of these processes include glucocorticoids, insulin-like growth factors, various cytokines, insulin, and leptin. Interactions among these axes have important implications in their influence on relative fat and lean deposition and the efficiency of energy utilization in growth and development. As research progresses to better clarify the interactions among adipose tissue depots and muscle of different fiber types, pathways will become better understood, ultimately leading to the optimized management of fat and lean growth in domestic livestock species. This review will focus on elements of intercellular signaling, using data from cell culture studies to illustrate specific examples of signaling pathways between cells. (C) 2004 Elsevier Inc. All rights reserved.",
author = "Kokta, {T. A.} and Dodson, {M. V.} and A. Gertler and Hill, {R. A.}",
note = "Kokta, TA Dodson, MV Gertler, A Hill, RA Hill, Rodney A/C-4106-2012 Hill, Rodney A/0000-0001-9990-1113",
year = "2004",
doi = "10.1016/j.domaniend.2004.05.004",
language = "English",
volume = "27",
pages = "303--331",
journal = "Domestic Animal Endocrinology",
issn = "0739-7240",
publisher = "Elsevier",
number = "4",

}

Intercellular signaling between adipose tissue and muscle tissue. / Kokta, T. A.; Dodson, M. V.; Gertler, A.; Hill, R. A.

In: Domestic Animal Endocrinology, Vol. 27, No. 4, 2004, p. 303-331.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Intercellular signaling between adipose tissue and muscle tissue

AU - Kokta, T. A.

AU - Dodson, M. V.

AU - Gertler, A.

AU - Hill, R. A.

N1 - Kokta, TA Dodson, MV Gertler, A Hill, RA Hill, Rodney A/C-4106-2012 Hill, Rodney A/0000-0001-9990-1113

PY - 2004

Y1 - 2004

N2 - Adipose and muscle tissues undergo regulated growth and differentiation processes that are modulated by a wide range of factors. The interactions between myogenic cells and adipocytes play a significant role in growth and development, including the rate and extent of myogenesis, muscle growth, adipogenesis, lipogenesis/lipolysis, and in the utilization of energy substrates. Important hormones and growth factors involved in the regulation of these processes include glucocorticoids, insulin-like growth factors, various cytokines, insulin, and leptin. Interactions among these axes have important implications in their influence on relative fat and lean deposition and the efficiency of energy utilization in growth and development. As research progresses to better clarify the interactions among adipose tissue depots and muscle of different fiber types, pathways will become better understood, ultimately leading to the optimized management of fat and lean growth in domestic livestock species. This review will focus on elements of intercellular signaling, using data from cell culture studies to illustrate specific examples of signaling pathways between cells. (C) 2004 Elsevier Inc. All rights reserved.

AB - Adipose and muscle tissues undergo regulated growth and differentiation processes that are modulated by a wide range of factors. The interactions between myogenic cells and adipocytes play a significant role in growth and development, including the rate and extent of myogenesis, muscle growth, adipogenesis, lipogenesis/lipolysis, and in the utilization of energy substrates. Important hormones and growth factors involved in the regulation of these processes include glucocorticoids, insulin-like growth factors, various cytokines, insulin, and leptin. Interactions among these axes have important implications in their influence on relative fat and lean deposition and the efficiency of energy utilization in growth and development. As research progresses to better clarify the interactions among adipose tissue depots and muscle of different fiber types, pathways will become better understood, ultimately leading to the optimized management of fat and lean growth in domestic livestock species. This review will focus on elements of intercellular signaling, using data from cell culture studies to illustrate specific examples of signaling pathways between cells. (C) 2004 Elsevier Inc. All rights reserved.

U2 - 10.1016/j.domaniend.2004.05.004

DO - 10.1016/j.domaniend.2004.05.004

M3 - Article

VL - 27

SP - 303

EP - 331

JO - Domestic Animal Endocrinology

JF - Domestic Animal Endocrinology

SN - 0739-7240

IS - 4

ER -