Neonatal calf diarrhoea can have a severe impact on health and growth of the individual affected. It also leads to significant economic losses in herds with high disease incidence. This case report documents theinvestigation and follow-up of a dairy herd with increased incidence of neonatal diarrhoea and scours related mortality of calves. It also reflects how managing the expansion of a herd inappropriately can cause several losses, particularly in young stock. Treatment of individual sick animals, corrective and preventive measures are also discussed. It is also highlighted that a continuous monitoring programme of the progress of the herd and checking that recommended practices continue once the incidence of diarrhoea decreases is vital for preventing a recurrence of a following outbreak.