Investigation of salbutamol enantiomer deposition in epithelial lining fluid in horses

Glenn A Jacobson; Kate Robson; Sharanne Raidal

Abstract

Beta2-agonists are chiral compounds, typically administered as 50:50 racemic mixtures of two enantiomers (stereoisomers denoted by R- and S- descriptors); molecules with non- superimposable mirror images analogous to right and left hands. Despite salbutamol (SALB) being used for over 40 years, there is surprisingly little information known about the enantioselective bronchopulmonary pharmacokinetics.

Original language	English
Pages	76-76
Number of pages	1
Publication status	Published - 2015
Event	APSA-ASCEPT 2015 Joint Scientific Meeting - Hotel Grand Chancellor , Hobart, Australia Duration: 29 Nov 2015 → 02 Dec 2015 https://www.asceptasm.com/2015-annual-scientific-meeting/program-2015/ (Conference website)

Conference

Conference	APSA-ASCEPT 2015 Joint Scientific Meeting
Abbreviated title	Drugs to Medicines: Up Close and Personal
Country	Australia
City	Hobart
Period	29/11/15 → 02/12/15
Other	Australian Pharmaceutical Science Association (APSA) & Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Joint Scientific Meeting 2015
Internet address	https://www.asceptasm.com/2015-annual-scientific-meeting/program-2015/ (Conference website)

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title = "Investigation of salbutamol enantiomer deposition in epithelial lining fluid in horses",

abstract = "Beta2-agonists are chiral compounds, typically administered as 50:50 racemic mixtures of two enantiomers (stereoisomers denoted by R- and S- descriptors); molecules with non- superimposable mirror images analogous to right and left hands. Despite salbutamol (SALB) being used for over 40 years, there is surprisingly little information known about the enantioselective bronchopulmonary pharmacokinetics. ",

author = "Jacobson, {Glenn A} and Kate Robson and Sharanne Raidal",

note = "Imported on 03 May 2017 - DigiTool details were: publisher = 2015. Event dates (773o) = 29 Nov - 2 Dec 2015; Parent title (773t) = APSA-ASCEPT 2015 Joint Scientific Meeting (Australian Pharmaceutical Science Association (APSA) & Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Joint Scientific Meeting 2015).; APSA-ASCEPT 2015 Joint Scientific Meeting, Drugs to Medicines: Up Close and Personal ; Conference date: 29-11-2015 Through 02-12-2015",

year = "2015",

language = "English",

pages = "76--76",

url = "https://www.asceptasm.com/2015-annual-scientific-meeting/program-2015/",

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T1 - Investigation of salbutamol enantiomer deposition in epithelial lining fluid in horses

AU - Jacobson, Glenn A

AU - Robson, Kate

AU - Raidal, Sharanne

N1 - Imported on 03 May 2017 - DigiTool details were: publisher = 2015. Event dates (773o) = 29 Nov - 2 Dec 2015; Parent title (773t) = APSA-ASCEPT 2015 Joint Scientific Meeting (Australian Pharmaceutical Science Association (APSA) & Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Joint Scientific Meeting 2015).

PY - 2015

Y1 - 2015

N2 - Beta2-agonists are chiral compounds, typically administered as 50:50 racemic mixtures of two enantiomers (stereoisomers denoted by R- and S- descriptors); molecules with non- superimposable mirror images analogous to right and left hands. Despite salbutamol (SALB) being used for over 40 years, there is surprisingly little information known about the enantioselective bronchopulmonary pharmacokinetics.

AB - Beta2-agonists are chiral compounds, typically administered as 50:50 racemic mixtures of two enantiomers (stereoisomers denoted by R- and S- descriptors); molecules with non- superimposable mirror images analogous to right and left hands. Despite salbutamol (SALB) being used for over 40 years, there is surprisingly little information known about the enantioselective bronchopulmonary pharmacokinetics.

UR - https://www.asceptasm.com/2015-annual-scientific-meeting/program-2015/

UR - https://www.asceptasm.com/wp-content/uploads/2015/03/APSA-ASCEPT-Book-of-oral-abstracts3.pdf?x82003

UR - https://www.asceptasm.com/wp-content/uploads/2015/03/ASPA-ASCEPT-Program-FINAL2.pdf?x82003

M3 - Abstract

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T2 - APSA-ASCEPT 2015 Joint Scientific Meeting

Y2 - 29 November 2015 through 2 December 2015

ER -