TY - JOUR
T1 - Is there immunity to Schistosoma japonicum?
AU - Ross, Allen G.P.
AU - Sleigh, Adrian C.
AU - Li, Yuesheng S.
AU - Williams, Gail M.
AU - Aligui, Gemiliano D.L.
AU - McManus, Don P.
N1 - Funding Information:
Our work has been supported by the National Health and Medical Research Council of Australia, the Tropical Health Program of the Australian Centre for International and Tropical Health and Nutrition, the University of Queensland Quality Funds for Interdisciplinary and International Research, the Australian Federal Department of Industry, Science and Tourism and the United Nations Development Program/World Bank/World Health Organization Special Program for Research and Training in Tropical Diseases. We acknowledge the work of Gary Waine who was involved in many of the studies described from our laboratory. We thank the Research Institute of Tropical Medicine in Manila (Remi Olveda) and the Hunan Institute of Parasitic Diseases (Chen Yan) for providing us with the epidemiological longitudinal data. We also thank Simon Forsyth for figure preparation and Tracey Checkley for manuscript preparation.
PY - 2000/4/1
Y1 - 2000/4/1
N2 - The Oriental schistosome, Schistosoma japonicum, unlike the other two major schistosomes that infect humans (S. mansoni and S. haematobium), is a zoonotic species. The transmission dynamics and the potential effects of host-related regulatory factors, including immunity, are likely to be distinct for this parasite. Here, Allen Ross and collaborators from Australia, China and the Philippines discuss recently published and established epidemiological and laboratory data bearing on anti-infection immunity to Asian schistosomiasis, and contrast these findings with the emerging picture of development of anti-infection immunity against the African schistosomes. Implications for vaccines and other control strategies for schistosomiasis japonica are also discussed. Copyright (C) 2000 Elsevier Science Ltd.
AB - The Oriental schistosome, Schistosoma japonicum, unlike the other two major schistosomes that infect humans (S. mansoni and S. haematobium), is a zoonotic species. The transmission dynamics and the potential effects of host-related regulatory factors, including immunity, are likely to be distinct for this parasite. Here, Allen Ross and collaborators from Australia, China and the Philippines discuss recently published and established epidemiological and laboratory data bearing on anti-infection immunity to Asian schistosomiasis, and contrast these findings with the emerging picture of development of anti-infection immunity against the African schistosomes. Implications for vaccines and other control strategies for schistosomiasis japonica are also discussed. Copyright (C) 2000 Elsevier Science Ltd.
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U2 - 10.1016/S0169-4758(99)01621-X
DO - 10.1016/S0169-4758(99)01621-X
M3 - Review article
C2 - 10725903
AN - SCOPUS:0034177412
VL - 16
SP - 159
EP - 164
JO - Parasitology Today
JF - Parasitology Today
SN - 0169-4758
IS - 4
ER -
