LAMP based detection of SARS-CoV-2 with low-cost off-the-shelf components

Kamalalayam Rajan Sreejith, Muhammad Umer, Narshone Soda, Surasak Kasetsirikul, Muhammad J.A. Shiddiky, Nam Trung Nguyen

Research output: Book chapter/Published conference paperConference paperpeer-review

Abstract

This paper reports the design, development, and testing of a novel, yet simple and low-cost portable device for rapid SARS-CoV-2 detection. The device performs loop mediated isothermal amplification (LAMP) and provides visually distinguishable images of the fluorescence emitted from the samples. The device utilises an aluminium block embedded with a cartridge heater for isothermal heating of the sample and a single-board computer and camera for fluorescence detection. The device demonstrates promising results within 20 minutes using clinically relevant starting concentrations of the synthetic template.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1214-1215
Number of pages2
ISBN (Electronic)9781733419017
Publication statusPublished - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020) - Virtual, Online
Duration: 04 Oct 202009 Oct 2020
https://www.microtasconferences.org/microtas2020/ (Conference website)
https://www.microtasconferences.org/microtas2020/program/MicroTAS2020_Program.pdf (Final program)
https://cbmsociety.org/conference/proceedings_archive.html (Proceedings)

Publication series

NameMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020)
Period04/10/2009/10/20
OtherWe are delighted to announce the on-line microTAS 2020! MicroTAS 2020 is uniquely designed to suit the scientific and community-building needs of the microTAS community and beyond. We will be maintaining our strong tradition of excellent contributed papers from all over the world and featuring plenary and keynote speakers covering wide-ranging topics in miniaturized life science and chemical science tools! At this particular challenging time for the world, we aim at bring together smart minds to design solutions to the problems we all face. For more information, see FAQ page.
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