Misidentification of a rare species, cryptococcus laurentii, by commonly used commercial biochemical methods and matrix-assisted laser desorption ionization-time of flight mass spectrometry systems: Challenges for clinical mycology laboratories

Meng Xiao, Xin Fan, Xin Xin Chen, He Wang, Li Zhang, Zhi Peng Xu, Timothy Kudinha, Fanrong Kong, Ying Chun Xu

Research output: Contribution to journalArticle

5 Citations (Scopus)
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Abstract

Forty-two putative Cryptococcus laurentii isolates identified by the Vitek 2 system were collected in China. The gold standard, internal transcribed spacer (ITS) sequencing, confirmed that only two isolates were genuine C. laurentii. Bruker Biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry was able to identify the C. laurentii isolates with an expanded custom database.

Original languageEnglish
Pages (from-to)226-229
Number of pages4
JournalJournal of Clinical Microbiology
Volume54
Issue number1
DOIs
Publication statusPublished - Jan 2016

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