Model Studies on the Construction of Side Chains for CD Intermediates of Vitamin D

Richard Haynes; Wendy A. Loughlin

doi:10.1071/CH9950663

Model Studies on the Construction of Side Chains for CD Intermediates of Vitamin D

Richard Haynes, Wendy A. Loughlin

Rural Health Research Institute

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Application of Horner- Wittig methodology for the synthesis of vitamin D side chains was examined through selected model studies. A requirement for syn or threo α- hydroxy diphenylphosphine oxide intermediates was established. The successful conversion of the model phosphine oxide (7) into the alkene (13), which demonstrates the potential of this method, is described.

Original language	English
Pages (from-to)	663-668
Number of pages	6
Journal	Australian Journal of Chemistry
Volume	48
Issue number	3
DOIs	https://doi.org/10.1071/CH9950663
Publication status	Published - 1995

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10.1071/CH9950663

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abstract = "Application of Horner- Wittig methodology for the synthesis of vitamin D side chains was examined through selected model studies. A requirement for syn or threo α- hydroxy diphenylphosphine oxide intermediates was established. The successful conversion of the model phosphine oxide (7) into the alkene (13), which demonstrates the potential of this method, is described.",

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Model Studies on the Construction of Side Chains for CD Intermediates of Vitamin D

Abstract

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